Deregulation of H3K27 methylation in cancer.

Nature Genetics
Eva Martinez-Garcia, Jonathan D Licht

Abstract

A new study now reports recurrent somatic mutation of EZH2, a histone methyltransferase that modifies H3K27, in diffuse large B-cell lymphoma (DLBCL). There is now evidence for both increased and decreased activity of enzymes controlling H3K27 methylation in cancer, suggesting that a precise balance of this methylation is critical for normal cell growth.

References

Dec 24, 2002·Nature Immunology·I-Hsin SuAlexander Tarakhovsky
May 6, 2003·Journal of Cell Science·Monika LachnerThomas Jenuwein
Jun 10, 2004·British Journal of Cancer·S BamfordR Wooster
Feb 27, 2007·Cell·Tony Kouzarides
Nov 17, 2007·Cancer Research·Jindan YuArul M Chinnaiyan
Aug 30, 2008·Mutation Research·Jeffrey A Simon, Carol A Lange
Oct 22, 2008·Nature Cell Biology·Klaus H HansenKristian Helin
Mar 31, 2009·Nature Genetics·Gijs van HaaftenP Andrew Futreal

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Citations

Mar 13, 2012·Inflammatory Bowel Diseases·Melania Scarpa, Eleni Stylianou
Apr 26, 2011·Oncogene·J FüllgrabeB Joseph
Sep 21, 2010·Integrative Biology : Quantitative Biosciences From Nano to Macro·Xinyue Zhang, Jing Huang
Nov 17, 2010·Proceedings of the National Academy of Sciences of the United States of America·Christopher J SneeringerRobert A Copeland
Mar 8, 2012·Proceedings of the National Academy of Sciences of the United States of America·Tobias NeffScott A Armstrong
Feb 16, 2013·Assay and Drug Development Technologies·Jeffrey R SimardVioleta Yu
Aug 22, 2013·Genes & Development·Rab Prinjha, Alexander Tarakhovsky
Dec 24, 2010·Journal of Gastroenterology and Hepatology·Daisy P F Tsang, Alfred S L Cheng
Apr 3, 2012·Journal of Cell Science·Yannick D BenoitJean-François Beaulieu
Jul 19, 2011·PloS One·Bettina FussbroichFelix Hoppe-Seyler
Dec 1, 2011·Epigenomics·Nicole Engel, Andreas Rank
Dec 21, 2011·Experimental Cell Research·Päivi Peltomäki
Jun 19, 2012·Clinical Epigenetics·Elzbieta PorebaAnna Gozdzicka-Jozefiak
Sep 25, 2010·Leukemia Research·Sang Wook ParkSug Hyung Lee
Aug 6, 2010·Current Opinion in Genetics & Development·Claudia Köhler, Lars Hennig
Mar 10, 2016·Biochimica Et Biophysica Acta·Patrick M PerrigueJan Barciszewski
Aug 1, 2015·Cancer Science·Katsunori Semi, Yasuhiro Yamada
May 14, 2011·Chemical Biology & Drug Design·Victoria M RichonRobert A Copeland
Apr 6, 2011·Journal of Cellular Physiology·Francesco Paolo Fiorentino, Antonio Giordano
Oct 21, 2010·CA: a Cancer Journal for Clinicians·Rodolphe Taby, Jean-Pierre J Issa
Jul 1, 2011·International Journal of Cancer. Journal International Du Cancer·Tetsuhiro ChibaOsamu Yokosuka
Dec 4, 2012·Biology of the Cell·Alicia Cock-Rada, Jonathan B Weitzman
Jan 10, 2012·Molecular Carcinogenesis·Yuan ZhouXue-Jun Zhang
Apr 15, 2015·International Journal of Cancer. Journal International Du Cancer·Ping ZhangOlaf van Tellingen
Mar 1, 2012·Cell Cycle·Fábio PereiraMaría Jesús Larriba
Jun 21, 2012·The American Journal of Pathology·Laxmi G PellakuruAngelo M De Marzo
Jun 10, 2011·Blood·William VainchenkerOlivier A Bernard
Apr 24, 2016·Urologic Oncology·Jiajun WangJianming Guo
Apr 12, 2016·Journal of Cellular Physiology·Alireza RoostaeeJean-François Beaulieu
Aug 16, 2016·Clinical Lymphoma, Myeloma & Leukemia·Prithviraj Bose, Srdan Verstovsek
Jan 7, 2017·Epigenetics : Official Journal of the DNA Methylation Society·Eleonore Maury, Rintaro Hashizume

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