PMID: 6161969Jan 1, 1980Paper

Derivation and characterization of a monoclonal hybridoma antibody specific for human alpha-fetoprotein

Journal of Immunological Methods
Y K TsungE Alpert

Abstract

A monoclonal antibody specific for human alpha-fetoprotein (HAFP) was derived by the hybridoma technique. Spleen cells from mice immunized with pure HAFP were fused with a mouse myeloma cell line (P3x63-Ag-8) and an anti-HAFP secreting hybridoma cell line was cloned in soft agarose. The HAFP specific antibody was shown to be a monoclonal IgG1 subclass with extremely high avidity for HAFP.

References

Oct 1, 1979·Proceedings of the National Academy of Sciences of the United States of America·C C HarrisI C Hsu
Apr 19, 1980·The Medical Journal of Australia·D C Morrell

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Citations

Jan 1, 1984·Antonie van Leeuwenhoek·O T Schönherr, E H Houwink
Jul 15, 1982·Clinica Chimica Acta; International Journal of Clinical Chemistry·D J BrockV van Heyningen
Jan 1, 1993·Biochimie·A Karmali, A Domingos
Sep 1, 1983·European Journal of Cancer & Clinical Oncology·B MicheelJ Kopp
Sep 15, 1984·International Journal of Cancer. Journal International Du Cancer·R L VessellaP H Lange

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