Derivation and validation of a hospital all-cause 30-day readmission index

American Journal of Health-system Pharmacy : AJHP : Official Journal of the American Society of Health-System Pharmacists
Taylor M FranckowiakRaymond Yost

Abstract

The study derives and validates a 30-day hospital readmission risk index to predict a patient's likelihood of readmission, utilizing a health systems electronic medical record. A retrospective data extraction and analysis was conducted using data from the electronic medical record to identify risks of 30-day all-cause hospital readmission on adult patients admitted to a large multi-site health system. Univariate and multivariable logistic regression was performed on a derivation cohort of hospital admissions (n = 40,668) and analyzed 91 variables associated with 30-day hospital readmission. A 10-variable risk prediction equation was generated and validated in a second patient cohort (n = 7,820). The prediction index's discriminative ability was determined using the c-statistic, and calibration of the prediction index was assessed with the use of the Hosmer-Lemeshow test. The hospital all-cause thirty-day readmission index (HATRIX) identified 10 variables to be highly associated with 30-day readmission. The discriminative ability of the derived prediction equation was determined using the c-statistic and was calculated to be 0.73 (95% confidence interval [CI] 0.72-0.73) for the derivation cohort. The prediction equation was vali...Continue Reading

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Citations

May 10, 2020·American Journal of Health-system Pharmacy : AJHP : Official Journal of the American Society of Health-System Pharmacists·Sean M McConachiePierre Tannous
Nov 9, 2021·Computers, Informatics, Nursing : CIN·Mary Anne SchultzAlvin D Jeffery

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