Dermatofibrosarcoma protuberans in childhood: two case reports and review of the literature

Pediatric Hematology and Oncology
G GerliniL Borgognoni

Abstract

Dermatofibrosarcoma protuberans (DFSP) is a rare skin cancer with intermediate malignancy, characterized by a progressive local growth and a propensity for local recurrence. DFSP is most frequent in adults; however, in recent years, DFSP in childhood emerged to be more common than previously believed. Unfortunately DFSP in children may be misdiagnosed, leading to a delay in the treatment. The authors report two cases of childhood DFSP with unusual clinical presentation: a congenital nodular variant and an atrophic variant developed at 2 years of age, both with acral localization. They highlight the importance of an early diagnosis by pediatricians and dermatologists to ensure an appropriate complete excision and reduce the risks of recurrences.

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Citations

May 11, 2012·Pediatric and Developmental Pathology : the Official Journal of the Society for Pediatric Pathology and the Paediatric Pathology Society·Jennifer BlackLouis P Dehner
Nov 17, 2012·Actas dermo-sifiliográficas·M Valdivielso-Ramos, J M Hernanz
Apr 10, 2012·Actas dermo-sifiliográficas·M Valdivielso-Ramos, J M Hernanz
Jul 20, 2010·Annals of Diagnostic Pathology·Atif A AhmedLinda Cooley
Nov 21, 2009·Journal of the American Academy of Dermatology·W Elliot LoveJeremy S Bordeaux
Jul 12, 2012·Pediatric Dermatology·Rachel I KornikJoyce M Teng
Nov 22, 2011·International Journal of Dermatology·Cary ChisholmClay J Cockerell
Nov 27, 2014·Pediatric Dermatology·Marta Valdivielso-RamosJose Luis Rodriguez-Peralto
Dec 15, 2017·The American Journal of Surgical Pathology·Kabeer K ShahRajiv M Patel
May 3, 2011·Neurological Sciences : Official Journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology·Giuseppe GranataLuca Padua
May 20, 2016·Journal of Clinical Imaging Science·Aliya Sarhan Al BarwaniAsif Alrawi
Jan 24, 2012·Journal of Clinical Imaging Science·Joseph L GatlinMajid Khan
Mar 27, 2013·Journal of Pediatric Hematology/oncology·Ausilia M ManganoniPiergiacomo Calzavara-Pinton
Oct 18, 2016·Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [et Al.]·Garrett C LoweJerry D Brewer

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