Dermatoglyphics in von Recklinghausen neurofibromatosis

American Journal of Medical Genetics
R PallottaF Chiarelli

Abstract

We studied dermatoglyphic traits in 27 patients (12 males and 15 females) with neurofibromatosis type I (NF-1) to verify which characteristics may be considered typical of this disorder. The frequency of digital central pockets in the patients was significantly greater than in control individuals (P less than .005), but when we evaluated the sexes separately, the difference was significant only among females (P less than .002). The distribution of central pockets on the various fingers was significantly different in affected females, compared with normal controls, but only on fingers II (P less than .05), IV (P .002), and V (P less than .05). The quantitative finger tip pattern values and the total finger ridge count (TFRC) were always higher in the patients, as well as was the a-b ridge count. The latter was significantly increased only on the right hand in females (P less than .01). Among the patients, the atd angle values were increased on both hands of females and on the right hand in males, whereas both the ulnar index A'-d and the a-t' ridge counts were diminished. The frequency of high endings (5' or 5") of line A was increased in NF-1 patients on both hands. Like in previous investigations, our patients showed an increa...Continue Reading

References

Oct 1, 1986·American Journal of Medical Genetics·W VormittagV Scheiber
Jan 1, 1984·Acta geneticae medicae et gemellologiae·W Vormittag, M Weninger
Apr 1, 1981·Ophthalmology·R A Lewis, V M Riccardi
Jan 1, 1980·American Journal of Medical Genetics·P A Otto, P G Otto

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Citations

May 31, 2011·Seizure : the Journal of the British Epilepsy Association·Hsiang-Yao HsiehTony Wu
Dec 26, 2001·American Journal of Medical Genetics·R PallottaP Fusilli
Jan 9, 2001·American Journal of Medical Genetics·R PallottaP Fusilli

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