Dermatomyositis and mucinosis

International Journal of Dermatology
J del PozoE Fonseca

Abstract

Mucin deposition is a common feature in autoimmune collagen diseases including dermatomyositis. Nevertheless, clinical manifestations of mucinosis are uncommon in patients with dermatomyositis. Two cases of mucinosis associated with dermatomyositis are reported. A 53-year-old woman presented with symmetrical plaques on the upper limbs formed by the coalescence of small, violaceous papules. In addition, she showed the typical cutaneous and muscle features of dermatomyositis. A 44-year-old woman with dermatomyositis of 5 years' evolution developed linear, flesh-colored papules across the flexural creases of her palms and fingers. Skin biopsy of the upper limb lesions in the first patient showed epidermal changes compatible with dermatomyositis and dermal mucin deposition. Histopathologic examination of the palmar lesions of the second patient showed less intense epidermal changes of dermatomyositis and dermal mucin deposition. Mucin deposition in patients with dermatomyositis may have an unusual clinical presentation, and it should be considered in the differential diagnosis of atypical cutaneous lesions in these patients.

References

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Citations

Oct 22, 2003·Current Opinion in Rheumatology·Beth Santmyire-Rosenberger, Elizabeth M Dugan
Jan 4, 2012·Pediatric Dermatology·Suzanne D QuinterBeth A Drolet
Aug 2, 2011·The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society·Jessica S Kim, Victoria P Werth
Sep 27, 2013·Anais Brasileiros De Dermatologia·Maria Helena Sampaio FavaratoRicardo Fuller
Dec 9, 2014·Case Reports in Dermatological Medicine·Alexandra Caitlin Perel-Winkler, Chris T Derk
May 3, 2011·Journal of the American Academy of Dermatology·David FiorentinoLivia Casciola-Rosen
Mar 4, 2011·Medicina clínica·Segundo BujánJosep Maria Grau
Jan 1, 2016·Annales de dermatologie et de vénéréologie·R GoussotD Lipsker
Sep 1, 2009·Reumatología clinica·Isabel Bielsa Marsol
Jun 24, 2008·Journal of the American Academy of Dermatology·Anne M SeidlerNellie Konnikov
Feb 24, 2011·International Journal of Dermatology·Sheng Wang
Apr 21, 2004·Journal of the American Academy of Dermatology·Edward W CowenMary Gail Mercurio
Jul 5, 2017·Journal of Cutaneous Medicine and Surgery·Russell X WongRichard M Haber
Sep 1, 2015·The American Journal of Dermatopathology·Kourosh BeroukhimChandra N Smart
May 4, 2018·Rheumatology International·Ankur Kumar JindalSurjit Singh
Jun 12, 2008·Jornal brasileiro de pneumologia : publicaça̋o oficial da Sociedade Brasileira de Pneumologia e Tisilogia·Fernanda Manente MilanezEster Nei Aparecida Martins Coletta

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