Aug 12, 2009

Dermatomyositis-like muscle pathology in patients with chronic graft-versus-host disease

Muscle & Nerve
Jeffrey A AllenAnthony A Amato


Myositis is a rare complication of chronic graft-versus-host disease (cGVHD) following hematopoietic stem cell transplantation (HSCT). Almost all such patients have been reported to have polymyositis (PM). We describe clinical, pathologic, and molecular studies of 3 patients with cGVHD following allogeneic HSCT who developed myopathy. In each case, perifascicular atrophy, the pathognomonic histologic feature of dermatomyositis (DM), was observed.

  • References25
  • Citations10


  • References25
  • Citations10


Mentioned in this Paper

Surface Electromyography
Dermatomyositis, Childhood Type
Graft-vs-Host Disease
Soleus Muscle Structure
Hemopoietic Stem Cell Transplant
Myeloid Leukemia, Chronic

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