Descemet membrane endothelial keratoplasty as treatment for graft failure after descemet stripping automated endothelial keratoplasty

American Journal of Ophthalmology
Julia M WellerBjörn O Bachmann

Abstract

To investigate the outcome of Descemet membrane endothelial keratoplasty (DMEK) in patients with graft failure after Descemet stripping automated endothelial keratoplasty (DSAEK). Retrospective cohort study. setting: Institutional. Fifteen eyes of 15 patients that underwent DMEK for graft failure with corneal decompensation following DSAEK were analyzed; 15 eyes with primary DMEK for Fuchs corneal dystrophy were included as control group. Best-corrected visual acuity (BCVA), endothelial cell density (ECD), central corneal thickness (CCT), and rebubbling rate. DMEK surgery was successful in all cases of both groups. Mean BCVA (logMAR) before DMEK was 1.27 ± 0.34 in the DMEK after DSAEK group and 1.0 ± 0.40 in the Primary DMEK group. After DMEK, mean BCVA increased significantly to 0.23 ± 0.21 (P = .012, DMEK after DSAEK group) and 0.29 ± 0.23 (P = .042, Primary DMEK group) after 3 months. There were no significant differences in mean BCVA between both groups at each visit. The rebubbling rate was 13% in the DMEK after DSAEK group and 40% in the Primary DMEK group (P = .1). Mean CCT decreased significantly in both groups 1 month after DMEK (P < .05). Mean ECD and change of ECD did not differ significantly between both groups at e...Continue Reading

References

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Dec 30, 2014·Ophthalmology·Francis W Price, Marianne O Price

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Citations

Jul 18, 2016·American Journal of Ophthalmology·Andreas SchlöglJulia M Weller
Aug 16, 2016·American Journal of Ophthalmology·Friederike SchaubBjörn O Bachmann
Apr 18, 2018·European Journal of Ophthalmology·Raquel Esteves MarquesWalter Rodrigues
Oct 17, 2017·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Friederike SchaubLudwig M Heindl
Aug 3, 2021·Journal of Ophthalmology·Anna MachalińskaKrzysztof Safranow
Apr 17, 2021·Cornea·Isabella MoshiriBjörn Bachmann

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