Descemet stripping automated endothelial keratoplasty after failed penetrating keratoplasty

Cornea
Anisha JangiJohn A Seedor

Abstract

To report the rate of graft dislocation, surgical anatomic success, and postsurgical complications associated with Descemet stripping automated endothelial keratoplasty (DSAEK) after previous primary failed penetrating keratoplasty (PK). Institutional review board-approved, single-center, retrospective chart review study of 30 eyes of 30 patients with prior failed PK who underwent DSAEK with a minimum of 3 months follow-up. Primary outcomes measured included rates of anatomic success and failure, postoperative complications, lenticle size, visual acuity, intraocular pressure change, and a report of external factors that may affect success. Thirty eyes of 30 patients were identified. The primary dislocation rate was 16.7%. Five primary DSAEKs detached; 1 was successfully rebubbled in the office, 2 had repeat successful DSAEKs, and 2 failed on a second attempt and had a subsequent PK. Despite successful anatomic attachment, 1 eye had primary graft failure, 3 that cleared initially failed within 6 months, and 1 that successfully cleared had subsequent graft rejection resulting in failure at 6 months. The 2 eyes requiring PK were excluded from the visual outcomes analysis, leaving 28 eyes with successfully attached lenticles. At 3 ...Continue Reading

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Citations

Mar 28, 2013·Case Reports in Transplantation·Ka Wai Kam, Alvin L Young
Nov 26, 2015·Current Opinion in Ophthalmology·Helen L Kornmann, Steven J Gedde
Nov 13, 2015·American Journal of Ophthalmology·Shreyas RamamurthyPrashant Garg
Jan 13, 2015·Journal français d'ophtalmologie·K ZitteF Chiambaretta

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