Jan 1, 1975

Description of new mutant forms of erythrocyte glucose-6-phosphate dehydrogenase in man

Genetika
T L ShatskaiaG A Annenkov

Abstract

9 variants of human erythrocyte glucose-6-phosphate dehydrogenase (G6PD) were isolated from erythrocytes of patients with G6PD deficiency and partially purified according to WHO program for stanartization of methods for studying G6PD. The results of physico-chemical study of these enzymes (determination of electrophoretic mobility, kappaM for G6P and NADP, pH optimum and thermostability) permit tu consider 5 of them to be new mutations of G6PD previously not described in literature. The observed high geterogeneity of variants of G6PD in Azerbaijan is discussed.

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Mentioned in this Paper

Enzymes, antithrombotic
G6PD
Glucosephosphate Dehydrogenase
Glucose-6-phosphate Dehydrogenase Measurement, Quantitative
Enzymes for Treatment of Wounds and Ulcers
Specimen Type - Erythrocytes
Mutant
Red Blood Cell Count Measurement
NADP
Enzymes, hematological

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