Desflurane improves the throughput of patients in the PACU. A cost-effectiveness comparison with isoflurane

Canadian Journal of Anaesthesia = Journal Canadien D'anesthésie
Marc BeaussierAndré Lienhart

Abstract

In a pharmacoeconomic approach of anesthesia, postanesthesia care unit (PACU) occupancy can be chosen as a criteria of effectiveness to compare two anesthetic drugs with different rates of elimination and different costs of administration. Our objective was to develop a cost-effectiveness approach for the comparison of isoflurane (I) and desflurane (D). In this prospective observational study, 68 patients aged 18-70 received either D or I for maintenance of anesthesia for inpatient abdominal procedures. Length of stay (LOS) in PACU was collected by a blinded observer. After the relationship between duration of surgery and LOS in PACU had been established in the 68 observed patients, we estimated the PACU occupancy according to duration of surgery and time of admission in PACU using a computer model of 204 consecutive patients, based on the hypothesis of an exclusive use of either D or I. Outcome measures were direct costs of the anesthesia procedure and occupancy of the PACU. The direct cost of the anesthetic was significantly higher with D than with I. This represents an increase of CAN$ 2 708 for the 204 patients. PACU occupancy was reduced by at least one patient (out of five beds) during 26.1% of the time with D (P <0.01). ...Continue Reading

References

Jul 1, 1992·Canadian Journal of Anaesthesia = Journal Canadien D'anesthésie·P Dion
Feb 1, 1995·Journal of Clinical Anesthesia·J A Aldrete
Jan 1, 1995·Anesthesiology·F Dexter, J H Tinker
Sep 1, 1994·Journal of Clinical Anesthesia·P F White, L D White
May 11, 1996·BMJ : British Medical Journal·N Black
May 1, 1997·Anesthesiology·M F Watcha, P F White
May 23, 1998·Canadian Journal of Anaesthesia = Journal Canadien D'anesthésie·M BeaussierA Lienhart
Sep 5, 1998·Anesthesia and Analgesia·J P WaddleJ F Piccirillo
Oct 13, 1998·Anesthesia and Analgesia·D J PavlinH Keyes

❮ Previous
Next ❯

Citations

Apr 3, 2002·Canadian Journal of Anaesthesia = Journal Canadien D'anesthésie·Donald R Miller, Micheal Tierney
Mar 11, 2004·Canadian Journal of Anaesthesia = Journal Canadien D'anesthésie·Michael J TesslerIan Shrier
Jul 15, 2005·Best Practice & Research. Clinical Anaesthesiology·I Odin, P Feiss
Nov 6, 2009·Annales Françaises D'anesthèsie Et De Rèanimation·B Plaud
Jun 1, 2015·Anaesthesia Critical Care & Pain Medicine·J RaftC Meistelman
Nov 6, 2004·Canadian Journal of Anaesthesia = Journal Canadien D'anesthésie·Stephan K W SchwarzCraig R Ries
Jun 23, 2016·Anaesthesia Critical Care & Pain Medicine·Sébastien PonsonnardNathalie Nathan

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.