Desflurane vs. sevoflurane as the main inhaled anaesthetic for spontaneous breathing via a laryngeal mask for varicose vein day surgery: a prospective randomized study

Acta Anaesthesiologica Scandinavica
G B SarosJ Jakobsson

Abstract

Sevoflurane has become widely used in day surgery; however, desflurane may be a valuable alternative even in this setting. This study compares emergence from anaesthesia for day surgery with spontaneous breathing using either desflurane or sevoflurane. This prospective, randomized, single-blinded study examined 70 ASA III patients undergoing elective ambulatory varicose vein surgery. Primary endpoint was emergence time (cessation of anaesthetic gas to communicating). Secondary endpoints included post-operative pain, nausea, time to discharge, and patient satisfaction. Patients were anaesthetized according to a standardized protocol including multimodal analgesia and antiemetic therapy and were randomized to receive sevoflurane or desflurane as the main anaesthetic while breathing spontaneously through a laryngeal mask airway. Fresh gas flow was oxygen in air 1 : 2 l/min. Intra-operative anaesthesia was uneventful apart from airway irritation observed in 5/35 desflurane and 1/35 sevoflurane patients. Emergence was 25-40% faster in patients anaesthetized with desflurane. Pain and post-operative nausea and vomiting (PONV) were equally infrequent in both groups. Overall, patient satisfaction was high with no difference between the ...Continue Reading

References

Apr 4, 1998·Acta Anaesthesiologica Scandinavica·J C RaederT Buanes
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Citations

May 16, 2009·Journal of Anesthesia·Hwa-Yong ShinDuk-Kyung Kim
Dec 12, 2012·Journal of Anesthesia·Junzo TakedaUNKNOWN Baxter BLM-240 Study Team
Mar 20, 2010·Journal of Clinical Monitoring and Computing·H HeijbelJan Jakobsson
Oct 22, 2015·Canadian Journal of Anaesthesia = Journal Canadien D'anesthésie·Ikuomi MikuniHiroshi Iwasaki
Dec 23, 2011·Acta Anaesthesiologica Scandinavica·J Jakobsson
May 12, 2010·Paediatric Anaesthesia·Jerrold LermanUNKNOWN MAPS Investigators Group
Dec 30, 2014·European Journal of Anaesthesiology·Ana StevanovicMark Coburn
Dec 1, 2009·Korean journal of anesthesiology·In Gyu ChoiHong Seok Chae
Nov 10, 2006·Current Opinion in Anaesthesiology
Jul 11, 2007·Current Opinion in Anaesthesiology

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