Design and Implementation of a Transmit/Receive Ultrasound Phased Array for Brain Applications

IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control
Hao-Li LiuHairong Zheng

Abstract

Focused ultrasound phased array systems have attracted increased attention for brain therapy applications. However, such systems currently lack a direct and real-time method to intraoperatively monitor ultrasound pressure distribution for securing treatment. This study proposes a dual-mode ultrasound phased array system design to support transmit/receive operations for concurrent ultrasound exposure and backscattered focal beam reconstruction through a spherically focused ultrasound array. A 256-channel ultrasound transmission system was used to transmit focused ultrasonic energy (full 256 channels), with an extended implementation of multiple-channel receiving function (up to 64 channels) using the same 256-channel ultrasound array. A coherent backscatter-received beam formation algorithm was implemented to map the point spread function (PSF) and focal beam distribution under a free-field/transcranial environment setup, with the backscattering generated from a strong scatterer (a point reflector or a microbubble-perfused tube) or a weakly scattered tissue-mimicking graphite phantom. Our results showed that PSF and focal beam can be successfully reconstructed and visualized in free-field conditions and can also be transcraniall...Continue Reading

Citations

Nov 30, 2018·Physics in Medicine and Biology·Christopher N AcconciaKullervo Hynynen
Mar 14, 2020·Ultrasound in Medicine & Biology·Klazina KooimanChristy K Holland

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