Design and synthesis of HCV agents with sequential triple inhibitory potentials

Bioorganic & Medicinal Chemistry Letters
Tianmin ZhuWeitao Pan

Abstract

The union of HCV-796, a potent selective HCV NS5B polymerase inhibitor, and Ribavirin, a molecule with activities against a wide spectrum of viruses, resulted in a class of new anti-HCV agents with a sequential triple inhibitory mechanism.

References

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Dec 17, 2008·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Norman M KnetemanMarc Collett
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Oct 24, 2009·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Vinod K RustgiUNKNOWN MErimepodib TRiple cOmbination Study Group

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