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Design of a microfluidic device to quantify dynamic intra-nuclear deformation during cell migration through confining environments

Integrative Biology : Quantitative Biosciences From Nano to Macro

Nov 10, 2015

Patricia M DavidsonJan Lammerding

Abstract

The ability of cells to migrate through tissues and interstitial spaces is an essential factor during development and tissue homeostasis, immune cell mobility, and in various human diseases. Deformation of the nucleus and its associated lamina during 3-D migration is gathering increasin...read more

Mentioned in this Paper

HEK293 Cells
Interstitial Space
2-Dimensional
Cell Motility
Nuclear Lamina
Blade - plant part
Protoplasm
Environment
Time-Lapse Imaging
Neoplasms
2
96
Paper Details
References
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  • Citations21
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  • References42
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Design of a microfluidic device to quantify dynamic intra-nuclear deformation during cell migration through confining environments

Integrative Biology : Quantitative Biosciences From Nano to Macro

Nov 10, 2015

Patricia M DavidsonJan Lammerding

PMID: 26549481

DOI: 10.1039/c5ib00200a

Abstract

The ability of cells to migrate through tissues and interstitial spaces is an essential factor during development and tissue homeostasis, immune cell mobility, and in various human diseases. Deformation of the nucleus and its associated lamina during 3-D migration is gathering increasin...read more

Mentioned in this Paper

HEK293 Cells
Interstitial Space
2-Dimensional
Cell Motility
Nuclear Lamina
Blade - plant part
Protoplasm
Environment
Time-Lapse Imaging
Neoplasms
2
96

Related Papers

Paper Details
References
  • References42
  • Citations21
12345
  • References42
  • Citations21
123
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