Design of a robust Ru(salen) complex: aziridination with improved turnover number using N-arylsulfonyl azides as precursors

Chemical Communications : Chem Comm
Kazufumi OmuraTsutomu Katsuki

Abstract

A new robust fluorinated (OC)Ru(salen) complex was designed on the basis of an X-ray structure of its parent complex to show improved turnover numbers (up to 878) and enantioselectivities (up to 99%) in aziridination reactions using p-toluenesulfonyl (Ts) or p-nitrobenzenesulfonyl (Ns) azide as the nitrene precursor; the latter is synthetically advantageous since the Ns group is N-protecting and can be removed under mild conditions.

Citations

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