Design of symmetric-sweep spectral-spatial RF pulses for spectral editing

Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine
Charles H CunninghamJohn M Pauly

Abstract

Spectral-spatial RF (SSRF) pulses allow simultaneous selection in both frequency and spatial domains. These pulses are particularly important for clinical and research MR spectroscopy (MRS) applications for suppression of large water and lipid resonances. Also, the high bandwidth of the subpulses (5-10 kHz) greatly reduces the spatial-shift errors associated with different chemical shifts. However, the use of high-bandwidth subpulses along with enough spectral bandwidth to measure a typical range of metabolite frequencies (e.g., 300 Hz at 3 T) can require RF amplitudes beyond the limits of the RF amplifier of a typical scanner. In this article, a new method is described for designing nonlinear-phase 180 degrees SSRF pulses that can be used for spectral editing. The novel feature of the pulses is that the spectral profile develops as a symmetric sweep, from the outside edges of the spectral window towards the middle, so that coupled components are tipped simultaneously and over a short interval. Pulses were designed for lactate editing at 1.5 T and 3 T. The spectral and spatial spin-echo profiles of the new pulses were measured experimentally. Spectra acquired in phantom experiments showed a well-resolved, edited lactate doublet...Continue Reading

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Citations

May 22, 2010·AJR. American Journal of Roentgenology·Sadhna VermaJohn Kurhanewicz
Oct 18, 2008·Magnetic Resonance Imaging Clinics of North America·John Kurhanewicz, Daniel B Vigneron
May 20, 2008·Magnetic Resonance Imaging·Duan XuDaniel B Vigneron
Feb 4, 2014·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Thiele KobusTom W J Scheenen
Aug 30, 2008·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·May-Britt TessemJohn Kurhanewicz
Jul 31, 2008·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Stephen PickupJerry D Glickson
Jun 27, 2008·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Venkatesh ManiZahi A Fayad
Nov 30, 2012·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Jimin RenCraig R Malloy
Aug 14, 2013·NMR in Biomedicine·V Y ZhangJ Kurhanewicz
Jun 14, 2013·NMR in Biomedicine·Thiele KobusArend Heerschap
Jan 18, 2006·Magnetic Resonance Imaging·Duan XuDaniel B Vigneron
Jun 28, 2017·NMR in Biomedicine·Francisco M Martínez-SantiestebanTimothy J Scholl
Oct 13, 2006·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Venkatesh ManiZahi A Fayad
Aug 31, 2007·Journal of Magnetic Resonance Imaging : JMRI·Karen C Briley-SaeboZahi A Fayad
Apr 23, 2008·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Priti BalchandaniDaniel Spielman
Apr 22, 2005·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Charles H CunninghamJohn M Pauly
Mar 1, 2006·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Masayuki YamaguchiManabu Minami
Apr 4, 2017·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Jun MaWilliam A Grissom
Nov 1, 2015·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Rebecca E Feldman, Priti Balchandani
Jan 29, 2005·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Kim ButtsGarry E Gold

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