PMID: 7538620Feb 1, 1995Paper

Design of the EPC-9, a computer-controlled patch-clamp amplifier. 1. Hardware

Journal of Neuroscience Methods
F J Sigworth

Abstract

The EPC-9 patch-clamp amplifier is a digitally controlled analog device for recording currents in membrane patches and in small cells. It has neither front-panel controls nor internal trim adjustments; instead all gain, range-changing, transient cancellation, calibration and other functions are computer controlled. Novel aspects of the circuit design of this instrument are discussed, with special reference to the issues of allowing computer control of all functions.

References

Jul 1, 1987·Biophysical Journal·C M Armstrong, R H Chow
Dec 1, 1994·Computer Methods and Programs in Biomedicine·A Ring
Feb 1, 1995·Journal of Neuroscience Methods·F J SigworthE Neher

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Citations

Oct 2, 2004·European Biophysics Journal : EBJ·Sven IngebrandtAndreas Offenhäusser
Jan 9, 2007·Pflügers Archiv : European journal of physiology·Andreas NeefTobias Moser
Feb 1, 1995·Journal of Neuroscience Methods·F J SigworthE Neher
Aug 16, 2005·Biophysical Journal·Günter WrobelAndreas Offenhäusser
Jul 20, 2010·Journal of Neuroscience Methods·Pujitha WeerakoonFred J Sigworth
Jul 9, 2008·Journal of Enzyme Inhibition and Medicinal Chemistry·Kunal Roy, Asim Sattwa Mandal
Nov 28, 2014·Journal of Neurophysiology·Reid R HarrisonCraig Forest
Feb 13, 2013·Beilstein Journal of Organic Chemistry·Graham Cr Ellis-Davies
Jul 1, 2012·Molecular Informatics·Subhash Ajmani, Sudhir A Kulkarni
May 26, 2020·Philosophical Transactions. Series A, Mathematical, Physical, and Engineering Sciences·Chon Lok LeiGary R Mirams

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