PMID: 2096172Nov 1, 1990Paper

"Designer drugs"--a current perspective

The Journal of Emergency Medicine
D A Jerrard

Abstract

Since the late 1970s, in an effort to quench the ever burgeoning appetite for pharmacological substances of abuse and to satiate their own need for profit, unscrupulous chemists have set up clandestine laboratories to produce and market new drugs for street sale. Using fairly common industrial chemicals, they have altered or modified preexisting controlled substances such as fentanyl, meperidine, mescaline, amphetamine, and phencyclidine, producing derivatives of these parent compounds that, up until 1986, were able to temporarily elude the guidelines of the Federal Controlled Substances Act due to their new and unique chemical structures. Unsuspecting users continue to use the drugs recreationally. This article will present a comprehensive review of these "Designer Drugs" looking at historical data, pharmacokinetics, treatment, abuse trends, and some of the more recent additions to the social pharmacopoeia.

References

Jan 1, 1976·Clinical Toxicology·B FaumanP Rosen
Feb 1, 1978·Clinical Pharmacology and Therapeutics·R SchleimerG Henderson
Sep 28, 1978·The New England Journal of Medicine·K M JanA Bornstein
Mar 1, 1989·The Journal of Emergency Medicine·R W DerletR V Lord
May 1, 1989·Brain Research·W L WoolvertonL S Seiden
Oct 1, 1986·Journal of Psychoactive Drugs·A T Shulgin
Oct 1, 1986·Journal of Psychoactive Drugs·G Greer, R Tolbert
Oct 1, 1986·Journal of Psychoactive Drugs·J Downing
Dec 4, 1986·The New England Journal of Medicine·P B LucasR W Cowdry
Jun 1, 1981·Annals of Emergency Medicine·M M McCarronW A Goetz
Oct 1, 1981·Archives of Internal Medicine·D L Simpson, B H Rumack
Mar 1, 1965·Journal of Medicinal Chemistry·V H MADDOXR F PARCELL

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Citations

Oct 31, 2009·Journal of Medical Toxicology : Official Journal of the American College of Medical Toxicology·Lewis Nelson, Robert Schwaner
Nov 4, 2000·Pediatric Emergency Care·M Shannon
Nov 1, 2008·Emergency Medicine Australasia : EMA·Shaun L GreeneGeorge Braitberg
Oct 29, 2003·Child and Adolescent Psychiatric Clinics of North America·Ramon Solhkhah
Feb 1, 1994·Immunopharmacology and Immunotoxicology·R V HouseH N Bhargava
Sep 10, 2010·Journal of Psychopharmacology·Tibor M BruntWim van den Brink
Apr 7, 2020·Archives of Toxicology·Dino Luethi, Matthias E Liechti
May 2, 2017·Journal of Analytical Toxicology·Barry K LoganMarilyn A Huestis
Jan 31, 2021·Pharmacology, Biochemistry, and Behavior·M L Shawn Bates, Keith A Trujillo

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