Designing Decellularized Extracellular Matrix-Based Bioinks for 3D Bioprinting

Advanced Healthcare Materials
Alperen Abaci, Murat Guvendiren

Abstract

3D bioprinting is an emerging technology to fabricate tissues and organs by precisely positioning cells into 3D structures using printable cell-laden formulations known as bioinks. Various bioinks are utilized in 3D bioprinting applications; however, developing the perfect bioink to fabricate constructs with biomimetic microenvironment and mechanical properties that are similar to native tissues is a challenging task. In recent years, decellularized extracellular matrix (dECM)-based bioinks have received an increasing attention in 3D bioprinting applications, since they are derived from native tissues and possess unique, complex tissue-specific biochemical properties. This review focuses on designing dECM-based bioinks for tissue and organ bioprinting, including commonly used decellularization and decellularized tissue characterization methods, bioink formulation and characterization, applications of dECM-based bioinks, and most recent advancements in dECM-based bioink design.

References

Apr 8, 2003·Trends in Biotechnology·Vladimir MironovRoger R Markwald
Jun 26, 2004·Journal of Vascular Surgery·Patrick J SchanerPaul J Dimuzio
Nov 3, 2004·Biochimica Et Biophysica Acta·Annela M SeddonPaula J Booth
Mar 1, 2005·Journal of Biomedical Materials Research. Part B, Applied Biomaterials·M H ZhengD Wood
Aug 23, 2006·Cell·Adam J EnglerDennis E Discher
Dec 18, 2007·Seminars in Immunology·Stephen F Badylak, Thomas W Gilbert
Jan 1, 2009·Tissue Engineering. Part C, Methods·Shiri UrielEric M Brey
Jan 30, 2009·Biomaterials·Vladimir MironovRoger R Markwald
Jun 9, 2009·Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society·Patrick VavkenMartha M Murray
Jun 10, 2009·Journal of Materials Science. Materials in Medicine·Xiaochao DongDinghua Yi
Jul 18, 2009·Biomaterials·Jennifer M SingelynKaren L Christman
Aug 12, 2009·Biomaterials·Cyrille NorotteGabor Forgacs
Oct 23, 2009·Tissue Engineering. Part a·Tiffany L SellaroStephen C Strom
Nov 4, 2009·Tissue Engineering. Part C, Methods·Lothar KochBoris Chichkov
Feb 13, 2010·Biomaterials·Seiichi FunamotoAkio Kishida
Feb 17, 2010·Tissue Engineering. Part a·Karina H NakayamaAlice F Tarantal
May 19, 2010·Biomaterials·Ferry P W MelchelsDirk W Grijpma
Jul 16, 2010·Nature Medicine·Harald C OttJoseph P Vacanti
Sep 3, 2010·Biofabrication·Karoly JakabGabor Forgacs
Oct 12, 2010·Acta Biomaterialia·D Adam YoungKaren L Christman
Nov 26, 2010·Acta Biomaterialia·Birzabith Mendoza-NoveloJosé L Mata-Mata
Feb 8, 2011·Biomaterials·Peter M CrapoStephen F Badylak
Apr 20, 2011·Cells, Tissues, Organs·Thomas H PetersenLaura E Niklason
Jun 23, 2011·Journal of Cardiovascular Translational Research·Sonya B Seif-NaraghiKaren L Christman
Nov 22, 2011·Nanotechnology·Todd D JohnsonKaren L Christman
Dec 6, 2011·Biomaterials·Timothy J KeaneStephen F Badylak
Feb 14, 2012·Biophysical Journal·Mozhgan NazariHeiko Heerklotz
Apr 25, 2012·Annual Review of Chemical and Biomolecular Engineering·Cole A DeForest, Kristi S Anseth
Nov 20, 2012·Science·Brian Derby
Apr 3, 2013·Current Opinion in Biotechnology·Murat Guvendiren, Jason A Burdick
Jul 10, 2013·International Journal of Pharmaceutics·Jin Seon KwonMoon Suk Kim
Jul 23, 2013·The Annals of Thoracic Surgery·John D O'NeillGordana Vunjak-Novakovic

❮ Previous
Next ❯

Citations

Dec 17, 2020·Bioengineering·Panagiotis MallisEfstathios Michalopoulos
Apr 16, 2021·Chemical Reviews·Alina KirillovaMatthew L Becker
May 1, 2021·Viruses·Francisca ArezPaula M Alves
Jun 8, 2021·Regenerative Therapy·Wenhui ZhangShenghua Chen
Jun 12, 2021·Regenerative Medicine·Fei SunHongcan Shi
Jun 9, 2021·Biomedical Materials·Fatemeh HaghwerdiMohamadreza Baghaban Eslaminejad
Sep 4, 2021·Materials Science & Engineering. C, Materials for Biological Applications·Fahimeh TabatabaeiLobat Tayebi
Oct 14, 2021·Advanced Healthcare Materials·Erick Insuasti-CruzFrank Alexis

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.