Desloratadine 5 mg once daily improves the quality of life of patients with chronic idiopathic urticaria

Journal of the European Academy of Dermatology and Venereology : JEADV
J M LachapelleN Vastesaeger

Abstract

Chronic urticaria is known to debilitate a person's quality of life via sleep disruption, itching lesions, fatigue, social isolation, energy loss and emotional/sexual difficulties. Once-daily desloratadine significantly improved the signs and symptoms of CIU. Assess the effect of desloratadine 5 mg once daily on the quality of life of patients suffering of chronic idiopathic urticaria (CIU). Study population One-hundred twenty-one consecutive patients with CIU present for at least 6 weeks prior to inclusion and with a current flare of at least 3 weeks, were included in the study in 24 Belgian centres. The mean dermatology life quality index (DLQI) significantly decreased from baseline to day 7 and further to day 42. Sixty per cent and 77% of patients had a clinically significant change (i.e. a decrease of at least 2 points) at day 7 or day 42, respectively, as compared with that of day 0. Change in pruritus and size of the hives significantly correlated with the change in the score of the quality of life. One-third of patients experienced complete relief whereas in 1 of 10 patients no effect was experienced. Desloratadine significantly improves the quality of life of patients with chronic idiopathic urticaria as reflected by th...Continue Reading

References

May 1, 1994·Clinical and Experimental Dermatology·A Y Finlay, G K Khan
May 8, 1999·The British Journal of Dermatology·E PoonA Kobza-Black
Apr 11, 2001·The Journal of Allergy and Clinical Immunology·R S Geha, E O Meltzer
Nov 13, 2001·American Journal of Clinical Dermatology·E E Lee, H I Maibach
Jan 5, 2002·The Journal of Investigative Dermatology. Symposium Proceedings·T ZuberbierB M Henz
Jul 9, 2002·The British Journal of Dermatology·G YosipovitchC L Goh
Mar 29, 2003·Journal of the American Academy of Dermatology·Eugene MonroeUNKNOWN Desloratadine Uritcaria Study Group
Jun 12, 2003·European Journal of Internal Medicine·Jean Paul Ortonne

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Citations

Jan 30, 2008·The Journal of Experimental Medicine·Walid BeghdadiSalaheddine Mécheri
Nov 1, 2011·Expert Opinion on Pharmacotherapy·Jean-Paul Ortonne
Jul 25, 2008·Current Medical Research and Opinion·J-J Grob, J-M Lachapelle
May 15, 2009·Journal of the European Academy of Dermatology and Venereology : JEADV·M Augustin, S Ehrle
Oct 1, 2011·Journal of the European Academy of Dermatology and Venereology : JEADV·J-B LiuH Zhou
Nov 15, 2014·The Cochrane Database of Systematic Reviews·Maulina SharmaBen Carter
Oct 2, 2007·American Journal of Clinical Dermatology·Lawrence DuBuske
Dec 8, 2011·Anais Brasileiros De Dermatologia·Ana Paula Fusel de UeDominique Sanda Oliveira Vilarinho Sabbag
Dec 15, 2020·Dermatology Research and Practice·Sushil PaudelSudarshan Paudel

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