Destination nowhere: a potential dilemma with ventricular assist devices

ASAIO Journal : a Peer-reviewed Journal of the American Society for Artificial Internal Organs
K A Bramstedt

Abstract

Increasingly, ventricular assist devices (VADs) are used as destination therapy for those who are not candidates for heart transplantation. Although these devices can benefit patients by improving their functional status and quality of life, they can, in some cases, facilitate an end-point known as "destination nowhere." In such situations, patients and clinicians find themselves in medical limbo where the patient's net benefit is, in fact, a burden, or the continued use of the device has no utility in light of the goals of the technology. This article presents guidance for avoiding "destination nowhere," as well as guidance for ethical care when patients arrive at this juncture.

References

May 10, 2001·The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation·K A Bramstedt, N S Wenger
Sep 15, 2001·The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation·E F LewisL W Stevenson
Apr 1, 2004·The Surgical Clinics of North America·Stephen Westaby
Jul 5, 2006·The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation·Leslie W Miller, Katherine Lietz
May 2, 2007·Current Cardiology Reports·Mark C Bieniarz, Reynolds Delgado
May 11, 2007·Expert Review of Cardiovascular Therapy·Stavros G DrakosJohn N Nanas

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Citations

Aug 13, 2008·Philosophy, Ethics, and Humanities in Medicine : PEHM·Aaron G RizzieriJoan L McGregor
Apr 23, 2009·Current Opinion in Cardiology·Maria M Mountis, Randall C Starling
Dec 17, 2008·Current Opinion in Supportive and Palliative Care·Katrina A Bramstedt
Feb 18, 2016·Clinical Research in Cardiology Supplements·Detlev WillemsenJ Glatz
Oct 8, 2013·Journal of Pain and Symptom Management·Keith M SwetzMolly A Feely
Sep 8, 2010·The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation·Sally BrushAbdallah G Kfoury
Jun 30, 2010·Mayo Clinic Proceedings·Paul S MuellerDaniel P Sulmasy
Jun 1, 2010·The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation·Keith M SwetzSoon J Park
Sep 1, 2015·Anesthesiology Clinics·Allen N Gustin, Rebecca A Aslakson
Jun 1, 2017·Circulation·Jennifer L CookUNKNOWN American Heart Association Heart Failure and Transplantation Committee of the Council on Clinical Cardiology; Council on Car
Dec 10, 2009·Autism Research : Official Journal of the International Society for Autism Research·Benjamin E YerysLauren Kenworthy
Apr 18, 2019·Journal of Neuroimaging : Official Journal of the American Society of Neuroimaging·Kalea L CollettaCamilo R Gomez
Jun 7, 2011·ASAIO Journal : a Peer-reviewed Journal of the American Society for Artificial Internal Organs·Ralph J PetrucciJohn W Entwistle
May 23, 2019·Cambridge Quarterly of Healthcare Ethics : CQ : the International Journal of Healthcare Ethics Committees·Daniel P Sulmasy, Mariele A Courtois
Apr 3, 2014·Critical Care Nurse·Brian J O'Neill, Meredith W Kazer

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