PMID: 8950810Nov 1, 1996Paper

Destroying retroviruses from within

Trends in Microbiology
J D Boeke, B Hahn

Abstract

One strategy for neutralizing retroviral infectivity is to induce the incorporation of lethal fusion proteins, such as capsid protein-nuclease fusions, into the virion during the normal viral assembly process. Genes encoding such antiviral fusion proteins must be nontoxic to the host, lethal to the virus, and must be efficiently delivered to, and expressed in, appropriate target cells.

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Citations

Jun 17, 1999·Lancet·A MannsL La Grenade
Nov 3, 2001·Molecular Urology·N OkuiT Kitamura
Jun 25, 1998·Clinical Chemistry and Laboratory Medicine : CCLM·A SavarinoP Gupta
Oct 2, 2012·Future Virology·Robert Craigie
Jan 2, 2001·The Journal of Biological Chemistry·G Beterams, M Nassal

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