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Desulfurization of 2-thiouracil nucleosides: conformational studies of 4-pyrimidinone nucleosides

Bioorganic & Medicinal Chemistry

Mar 15, 2011

Karina KraszewskaElzbieta Sochacka

Abstract

4-Pyrimidinone ribofuranoside (H(2)o(4)U) and 4-pyrimidinone 2'-deoxyribofuranoside (dH(2)o(4)U) were synthesized by the oxidative desulfurization of parent 2-thiouracil nucleosides with m-chloroperbenzoic acid. The crystal structures of H(2)o(4)U and dH(2)o(4)U and their conformations ...read more

Mentioned in this Paper

Muscle Rigidity
Ethanol
Pyridines
Crystal - Body Material
Torsion (Malposition)
Nucleoside Analogs
Ethanol Measurement
Ninhydrin
Structure-Activity Relationship
Nucleic Acid Hybridization Procedure
Paper Details
References
  • References9
  • Citations4
1

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Desulfurization of 2-thiouracil nucleosides: conformational studies of 4-pyrimidinone nucleosides

Bioorganic & Medicinal Chemistry

Mar 15, 2011

Karina KraszewskaElzbieta Sochacka

PMID: 21396827

DOI: 10.1016/j.bmc.2011.02.008

Abstract

4-Pyrimidinone ribofuranoside (H(2)o(4)U) and 4-pyrimidinone 2'-deoxyribofuranoside (dH(2)o(4)U) were synthesized by the oxidative desulfurization of parent 2-thiouracil nucleosides with m-chloroperbenzoic acid. The crystal structures of H(2)o(4)U and dH(2)o(4)U and their conformations ...read more

Mentioned in this Paper

Muscle Rigidity
Ethanol
Pyridines
Crystal - Body Material
Torsion (Malposition)
Nucleoside Analogs
Ethanol Measurement
Ninhydrin
Structure-Activity Relationship
Nucleic Acid Hybridization Procedure

Related Papers

Paper Details
References
  • References9
  • Citations4
1
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