Detailed mtDNA genotypes permit a reassessment of the settlement and population structure of the Andaman Islands

American Journal of Physical Anthropology
S S BarikV R Rao

Abstract

The population genetics of the Indian subcontinent is central to understanding early human prehistory due to its strategic location on the proposed corridor of human movement from Africa to Australia during the late Pleistocene. Previous genetic research using mtDNA has emphasized the relative isolation of the late Pleistocene colonizers, and the physically isolated Andaman Island populations of Island South-East Asia remain the source of claims supporting an early split between the populations that formed the patchy settlement pattern along the coast of the Indian Ocean. Using whole-genome sequencing, combined with multiplexed SNP typing, this study investigates the deep structure of mtDNA haplogroups M31 and M32 in India and the Andaman Islands. The identification of a so far unnoticed rare polymorphism shared between these two lineages suggests that they are actually sister groups within a single haplogroup, M31'32. The enhanced resolution of M31 allows for the inference of a more recent colonization of the Andaman Islands than previously suggested, but cannot reject the very early peopling scenario. We further demonstrate a widespread overlap of mtDNA and cultural markers between the two major language groups of the Andaman...Continue Reading

References

Jan 1, 1991·Journal of Molecular Evolution·M Hasegawa, S Horai
Apr 9, 1981·Nature·S AndersonI G Young
Dec 2, 1999·Nature Genetics·L Quintana-MurciA S Santachiara-Benerecetti
Aug 5, 2000·American Journal of Human Genetics·J SaillardS Nørby
Dec 29, 2000·Nature·M IngmanU Gyllensten
Apr 20, 2001·Journal of Human Genetics·G FucharoenS Horai
Sep 13, 2001·BMC Genetics·N Maca-MeyerV M Cabrera
Apr 16, 2002·American Journal of Physical Anthropology·Yong-Gang YaoYa-Ping Zhang
Dec 13, 2002·American Journal of Human Genetics·Phillip EndicottAlan Cooper
Jan 2, 2003·Proceedings of the National Academy of Sciences of the United States of America·Dan MishmarDouglas C Wallace
Jan 22, 2003·American Journal of Human Genetics·T KivisildR Villems
Jan 28, 2003·Current Biology : CB·Kumarasamy ThangarajErika Hagelberg
Apr 8, 2003·European Journal of Human Genetics : EJHG·Richard CordauxMark Stoneking
Oct 4, 2003·Genome Research·Analabha BasuPartha P Majumder
Jun 11, 2004·Molecular Biology and Evolution·Neil HowellCorinna Herrnstadt
Mar 2, 2005·PLoS Biology·Hiroki OotaMark Stoneking
Apr 9, 2005·Molecular Biology and Evolution·Jonathan FriedlaenderD Andrew Merriwether
May 14, 2005·Science·Kumarasamy ThangarajLalji Singh
Sep 10, 2005·Proceedings of the National Academy of Sciences of the United States of America·D Andrew MerriwetherJonathan S Friedlaender
Sep 21, 2005·Genetics·Toomas KivisildPeter J Oefner
Jan 28, 2006·Science·Malliya Gounder PalanichamyYa-Ping Zhang
May 11, 2006·PLoS Biology·Alexei J DrummondAndrew Rambaut
Jun 17, 2006·BMC Genomics·Kumarasamy ThangarajLalji Singh
Jun 22, 2006·American Journal of Human Biology : the Official Journal of the Human Biology Council·Vikrant KumarB Mohan Reddy
Sep 20, 2006·Molecular Biology and Evolution·Catherine HillMartin Richards
Apr 5, 2007·Nature Protocols·Juan J Sanchez, Phillip Endicott
May 15, 2007·Proceedings of the National Academy of Sciences of the United States of America·Georgi HudjashovPeter Forster

❮ Previous
Next ❯

Citations

Oct 31, 2012·Journal of Biosciences·Rakesh TamangKumarasamy Thangaraj
Sep 26, 2009·Nature·David ReichLalji Singh
Oct 2, 2012·Investigative Genetics·Rakesh Tamang, Kumarasamy Thangaraj
Aug 8, 2009·PloS One·Kumarasamy ThangarajLalji Singh
Apr 12, 2011·Journal of Genetics and Genomics = Yi Chuan Xue Bao·Hua-Wei WangYa-Ping Zhang
Nov 6, 2013·American Journal of Physical Anthropology·Lyle W Konigsberg, Susan R Frankenberg
Sep 29, 2011·American Journal of Human Genetics·David ReichMark Stoneking
Aug 13, 2013·American Journal of Human Genetics·Priya MoorjaniLalji Singh
Nov 12, 2016·BMC Evolutionary Biology·Patricia MarreroVicente M Cabrera
Jan 26, 2018·Scientific Reports·Wibhu KutananMark Stoneking
Mar 26, 2010·Annals of Human Biology·Michael D PetragliaChris Clarkson
Nov 10, 2018·Science·J Víctor Moreno-MayarEske Willerslev
Oct 13, 2021·Genes and Immunity·Prajjval Pratap SinghGyaneshwer Chaubey

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.