Detailed Phytochemical Characterization of Bergamot Polyphenolic Fraction (BPF) by UPLC-DAD-MS and LC-NMR

Journal of Agricultural and Food Chemistry
Carmen FormisanoOrazio Taglialatela-Scafati

Abstract

Bergamot ( Citrus bergamia) is cultivated in Southern Italy almost exclusively to produce the prized essential oil, a top note in several perfumes. The juice of bergamot, until recently poorly studied, is the object of a growing scientific interest due to its claimed activity to treat metabolic syndrome. The aim of this investigation was a detailed characterization of bergamot juice polyphenolic fraction (BPF) based on a UPLC-DAD-MS analysis complemented by preparative chromatographic separations, followed by NMR characterization of the isolated compounds. The combination of these techniques efficiently covered different classes of secondary metabolites, leading to the identification of 39 components, several of which had never been reported from bergamot. One of them, bergamjuicin (35), is a new flavanone glycoside, whose structure has been determined by MS and NMR techniques. The reported results could provide a guide for future routine analyses of BPF, a material of great nutraceutical and industrial interest.

References

Sep 18, 2001·Journal of Agricultural and Food Chemistry·R G CameronK Grohmann
Dec 28, 2002·Journal of Natural Products·Rita AquinoLuca Rastrelli
Apr 25, 2003·Zeitschrift Für Naturforschung. C, a Journal of Biosciences·Hasan KirmizibekmezIhsan Caliş
Nov 25, 2003·Phytochemistry·Namboole Moses MunkombweNametso Morebodi
Jan 5, 2006·Journal of Agricultural and Food Chemistry·Giuseppina MandalariKeith W Waldron
Jan 24, 2006·Bioscience, Biotechnology, and Biochemistry·Yoichi NogataHideaki Ohta
May 25, 2006·Journal of Agricultural and Food Chemistry·Giuseppe GattusoUgo Leuzzi
Oct 27, 2007·Journal of Agricultural and Food Chemistry·Giuseppe GattusoUgo Leuzzi
Mar 19, 2015·Frontiers in Pharmacology·Michele NavarraGioacchino Calapai
Nov 16, 2016·The Journal of Nutritional Biochemistry·Antonio BrunoMaria Rosaria Anna Muscatello
Nov 25, 2016·BioMed Research International·Mariangela RondanelliSimone Perna

❮ Previous
Next ❯

Citations

Dec 18, 2020·Phytochemical Analysis : PCA·Ying-Jie HeXiao-Dong Luo

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.