Detecting and quantifying activity/inflammation in localized scleroderma with thermal imaging

Skin Research and Technology : Official Journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI)
I Ranosz-JanickaL Brzezińska-Wcisło

Abstract

The disease phase in localized scleroderma (LoS) is commonly assessed by clinical investigation using the LoS cutaneous assessment tool (LoSCAT). There is a need for more objective methods for assessing the degree of activity/inflammation in LoS. The aim of our work was to evaluate the correlation between severity of the LoS lesions scored using LoSCAT and the degree of hyperthermia observed with infrared thermography (IRT). The LoS lesions were examined using the LoSCAT and IRT independently by two examiners. The average temperature (Tavg) of the LoS lesional dermis were measured in the area of each lesion with the highest score for erythema (ER), skin thickness (ST), dermal atrophy (DAT) and subcutaneous atrophy (SAT). Measurements were compared to the contralateral healthy skin. The difference of the Tavg (ΔTavg) was calculated between each lesion and its normal control. One hundred and four LoS lesions were examined in 40 adults. Thirty-one lesions were erythematous, 26 were sclerotic, 35 presented as atrophy of the dermis and 11 as atrophy of the subcutaneous tissue. The sensitivity and specificity of IRT for detecting activity/inflammation were 80.7% and 86.3%, respectively. The positive predictive value was 71%, negative...Continue Reading

References

Oct 2, 2007·Arthritis and Rheumatism·Lisa WeibelJohn I Harper
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Dec 13, 2016·International Journal of Dermatology·Maria T Garcia-RomeroElena Pope

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Citations

Jun 4, 2019·Current Opinion in Pediatrics·Adriana G Peña-Romero, Maria T García-Romero
Dec 19, 2020·The American Journal of Dermatopathology·Yvonne E ChiuOlayemi Sokumbi
Apr 28, 2021·Experimental Dermatology·Mariane Massufero VergilioGislaine Ricci Leonardi
Jul 18, 2021·Pediatric Dermatology·Jacquelyn R Sink, Yvonne E Chiu
Jan 19, 2022·Journal of Cosmetic Dermatology·Mariane Massufero VergilioGislaine Ricci Leonardi

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