Detecting comorbid substance misuse among people with schizophrenia in the community: a study comparing the results of questionnaires with analysis of hair and urine

Schizophrenia Research
M A McPhillipsK Clark

Abstract

Substance misuse among people with schizophrenia is thought to be common and to adversely affect the outcome of the illness. The shortcomings of studies in this area include patient samples that are not epidemiologically-based, and methods for detecting substance misuse that have serious limitations. We investigated the frequency and severity of substance misuse among people with schizophrenia living in the community in London. Interviews were conducted with a community-based sample of 39 people with schizophrenia aged 35 years or less, living in Inner London. The assessments included ratings of psychopathology, movement disorders and substance misuse, and co-informant histories. Urine and hair specimens were analysed for a range of substances. Urine samples were collected from 37 patients and hair samples were provided by 36 patients. Comorbid substance misuse was reported or detected in 63% of the sample. The information elicited using a structured questionnaire for both informants and subjects represented an under-estimate of psychostimulant misuse and opiate misuse compared with the results obtained by hair or urine analysis. Hair analysis revealed that 12 (33%) of those patients providing samples had covertly abused amphet...Continue Reading

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Citations

Jul 6, 2000·European Psychiatry : the Journal of the Association of European Psychiatrists·P Batel
Aug 2, 2006·The British Journal of Psychiatry : the Journal of Mental Science·L HidesR McD Young
Jan 5, 2002·Journal of Addictive Diseases·J ModestinS Christen
Mar 20, 2014·Annals of General Psychiatry·Hiranya WijesunderaVaruni A de Silva
Oct 10, 2013·Journal of Child Psychology and Psychiatry, and Allied Disciplines·Paul A Tiffin, Patrick Welsh
Feb 21, 2009·Clinical Psychology & Psychotherapy·Catriona RalleyAnja Wittkowski
Apr 15, 2015·Schizophrenia Research·Lauren Spriggens, Leanne Hides
Sep 9, 2008·European Journal of Pharmacology·Zahra NourianTorsten Kristensen
Apr 4, 2009·European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology·Ayelet AvitalRoni Shiloh
Jun 26, 2007·Revista de saúde pública·Lilian R C RattoAndré Gulinelli
Jun 2, 2007·The British Journal of Psychiatry : the Journal of Mental Science·Jennifer H BarnettPeter B Jones
Feb 2, 1999·The British Journal of Psychiatry : the Journal of Mental Science·M A McPhillipsT R Barnes
Jul 9, 2008·Drug and Alcohol Review·Leanne HidesRoss McD Young

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