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Detecting translational regulation by change point analysis of ribosome profiling datasets

bioRxiv

Mar 5, 2014

Anze ZupanicDaryl Pierson Shanley

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Abstract

Ribo-Seq maps the location of translating ribosomes on mature mRNA transcripts. While ribosome density is constant along the length of the mRNA coding region, it can be altered by translational regulatory events. In this study, we developed a method to detect translational regulation of...read more

Mentioned in this Paper

Regulation of Translation
Study
Protein Isoforms
Ribosomes
Post-Transcriptional Regulation
Profile (Lab Procedure)
Open Reading Frames
Genome
RNA
Atf4 protein, mouse
2
4
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  • Detecting translational regulation by change point analysis of ribosome profiling datasets

    bioRxiv

    Mar 5, 2014

    Anze ZupanicDaryl Pierson Shanley

    PMID: 990003210

    DOI: 10.1101/003210

    Abstract

    Ribo-Seq maps the location of translating ribosomes on mature mRNA transcripts. While ribosome density is constant along the length of the mRNA coding region, it can be altered by translational regulatory events. In this study, we developed a method to detect translational regulation of...read more

    Mentioned in this Paper

    Regulation of Translation
    Study
    Protein Isoforms
    Ribosomes
    Post-Transcriptional Regulation
    2
    4

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