Detection and molecular characterization of a novel large Babesia species in a dog

Veterinary Parasitology
Adam J BirkenheuerEdward B Breitschwerdt

Abstract

Babesia canis has generally been considered the only large Babesia to infect dogs. Here we describe the molecular characterization of a large Babesia species that was detected in the blood and bone marrow of a dog with clinical and hematological abnormalities consistent with babesiosis. Analysis of the 18S rRNA genes revealed a unique sequence that shared 93.9% sequence identity with B. bigemina and 93.5% sequence identity with B. caballi, compared to 91.2-91.6% identity with B. canis canis, B. c. vogeli, and B. c. rossi. Cross-reactive antibodies against B. canis, B. gibsoni (Asian genotype), or B. gibsoni (California genotype) antigens were not detected in acute or convalescent serum samples. The dog was treated with imidocarb diproprionate, which resulted in the resolution of clinical signs, and subsequently Babesia DNA was not detectable by PCR in post-treatment samples. The organism described in this report represents a genetically unique large Babesia sp. and is the eighth genetically distinct piroplasm capable of infecting the domestic dog.

References

Jan 1, 1992·Memórias do Instituto Oswaldo Cruz·P Brasseur, A Gorenflot
Jan 1, 1989·The Veterinary Quarterly·G UilenbergA A Spanjer
Feb 1, 1994·Parasitology·M T AllsoppB A Allsopp
May 1, 1996·Veterinary Parasitology·B D LewisD T De Waal
Apr 13, 2000·Veterinary Parasitology·M ZahlerR Gothe
Jun 29, 2001·International Journal for Parasitology·A M KjemtrupP A Conrad
Jul 20, 2002·Journal of the American Veterinary Medical Association·James H MeinkothMichael D Lorenz
Apr 30, 2003·Veterinary Parasitology·A Criado-FornelioJ C Barba-Carretero

❮ Previous
Next ❯

Citations

Jun 28, 2014·Parasitology International·Diego Fernando EirasGastón Moré
May 12, 2009·Parasites & Vectors·Peter J Irwin
Sep 29, 2005·Vector Borne and Zoonotic Diseases·V A RarO V Morozova
Jun 1, 2005·Veterinary Parasitology·Tshepo P MatjilaFrans Jongejan
Sep 30, 2005·Journal of the American Veterinary Medical Association·Adam J BirkenheuerEdward B Breitschwerdt
Oct 9, 2012·Journal of the American Veterinary Medical Association·Devorah A Marks StoweCarol B Grindem
Jan 24, 2012·Trends in Parasitology·Vesna MatijatkoTheo P Schetters
Jul 23, 2011·Veterinary Parasitology·Bruno Chomel
May 17, 2011·Veterinary Parasitology·Laia Solano-Gallego, Gad Baneth
Oct 12, 2010·The Veterinary Clinics of North America. Small Animal Practice·Peter J Irwin
Apr 10, 2010·Veterinary Parasitology·Øivind ØinesHege Brun-Hansen
Feb 27, 2010·Veterinary Parasitology·Pierre-Hugues PitelGuillaume Fortier
Nov 26, 2009·The Veterinary Clinics of North America. Small Animal Practice·Patricia J Holman, Karen F Snowden
Jul 28, 2009·Veterinary Parasitology·R CassiniM Pietrobelli
Apr 16, 2009·International Journal for Parasitology·Relja BeckSimone M Cacciò
Sep 13, 2008·Veterinary Parasitology·Diego Fernando EirasLeonhard Schnittger
Aug 9, 2008·Veterinary Parasitology·P T MatjilaB L Penzhorn
Jul 8, 2008·Veterinary Parasitology·Luís CardosoGad Baneth
Dec 18, 2007·Veterinary Parasitology·Lauren E LehtinenPatricia J Holman
Aug 26, 2015·Ticks and Tick-borne Diseases·Bronislava VíchováBranislav Peťko
Feb 10, 2007·Veterinary Parasitology·Masahiro YamasakiYoshimitsu Maede
Jul 28, 2011·Veterinary Clinical Pathology·Robin W AllisonMason V Reichard
Dec 17, 2009·Journal of Veterinary Internal Medicine·L E SikorskiM P Littman
Mar 17, 2010·Journal of Veterinary Emergency and Critical Care·Ashley L AyoobJennifer Prittie
Apr 9, 2014·Ticks and Tick-borne Diseases·Barbara C ShockMichael J Yabsley
Aug 12, 2006·The Veterinary Journal·Rafael Ruiz de GopeguiLuciano Espino
Apr 6, 2006·Veterinary Parasitology·Aynur GülanberBernard Carcy
Mar 9, 2006·Veterinary Parasitology·Anne M Kjemtrup, Patricia A Conrad
Mar 4, 2006·Veterinary Parasitology·Gerrit Uilenberg
Nov 1, 2005·Experimental Parasitology·Anthony R MartinGraeme K Brown
Aug 9, 2012·Infection, Genetics and Evolution : Journal of Molecular Epidemiology and Evolutionary Genetics in Infectious Diseases·Leonhard SchnittgerDavid A Morrison
Nov 25, 2014·The Journal of Parasitology·Khaled Mohamed El-DakhlyYasuhiro Takashima
Feb 18, 2014·International Journal for Parasitology. Parasites and Wildlife·Michael J Yabsley, Barbara C Shock
Jun 13, 2016·Parasites & Vectors·Laia Solano-GallegoGuadalupe Miró
Oct 1, 2009·American Journal of Physical Medicine & Rehabilitation·John C King
Jul 27, 2012·Revista brasileira de parasitologia veterinária = Brazilian journal of veterinary parasitology : Órgão Oficial do Colégio Brasileiro de Parasitologia Veterinária·Tatiana Didonet LemosNádia Regina Pereira Almosny
Dec 15, 2011·Revista brasileira de parasitologia veterinária = Brazilian journal of veterinary parasitology : Órgão Oficial do Colégio Brasileiro de Parasitologia Veterinária·Sabrina Castilho DuarteGuido Fontgalland Coelho Linhares

❮ Previous
Next ❯

Related Concepts

Related Feeds

Babesiosis (ASM)

Babesiosis is caused by parasites of the genus babesia, which are transmitted in nature by the bite of an infected tick. Discover the latest research on babesiosis here.

Brucellosis (ASM)

Brucellosis is a bacterial infection caused by members of the genus brucella and remains one of the world's major zoonotic diseases. Discover the latest research on Brucellosis here.

Babesiosis

Babesiosis is caused by parasites of the genus babesia, which are transmitted in nature by the bite of an infected tick. Discover the latest research on babesiosis here.

Anemia

Anemia develops when your blood lacks enough healthy red blood cells. Anemia of inflammation (AI, also called anemia of chronic disease) is a common, typically normocytic, normochromic anemia that is caused by an underlying inflammatory disease. Here is the latest research on anemia.

Brucellosis

Brucellosis is a bacterial infection caused by members of the genus brucella and remains one of the world's major zoonotic diseases. Discover the latest research on Brucellosis here.