PMID: 20654215Jul 27, 2010Paper

Detection of adenovirus and herpes simplex virus in the tears of chronic conjunctivitis

[Zhonghua yan ke za zhi] Chinese journal of ophthalmology
Ying Jin, Jing Hong

Abstract

To analyze the tears of outpatients who had chronic conjunctivitis infected adenovirus (AdV) and (or) herpes simplex virus (HSV). It was an experimental study. 81 patients with chronic conjunctivitis (adult 66 cases, children 15 cases), 9 cases with acute viral conjunctivitis and 30 healthy control cases. To collect their tears, use polymerase chain reaction (PCR) to detect herpes simplex virus and adenovirus, and analyze the results of PCR, clinical symptoms and signs. In patients with chronic conjunctivitis, adenovirus-positive rate was 32.1% (26/81) and herpes simplex virus-positive rate was 30.9% (25/81). In children patients with chronic conjunctivitis, the adenovirus-positive rate was 33.3% (5/15) and herpes simplex virus-positive rate was 13.3% (2/15). In adult group, the adenovirus-positive rate was 31.8% (21/66) and herpes simplex virus-positive rate was 34.8% (23/66). In patients who underwent acute conjunctivitis, the adenovirus-positive rate was 61.5% (16/26). It has statistical differences (chi2=16.884, P<0.01) with no acute conjunctivitis patients. The herpes simplex virus-positive rate was 42.3% (11/26). It has statistical differences (chi2=5.351, P=0.021) with no acute conjunctivitis patients. The positive rate ...Continue Reading

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