Detection of antigen specific circulating immune complexes in Indian kala-azar.

Annals of Tropical Medicine and Parasitology
L Srivastava

Abstract

The sera of active and treated cases of kala-azar were tested for circulating immune complexes (CIC) by antigen-specific enzyme linked immunosorbent assay (ELISA). All (100%) of proved cases had elevated CIC; 64.3% of clinically diagnosed cases and 58.8% of treated cases were also positive for CIC. A fall in the level of CIC was observed after treatment. Detection of antigen-specific CIC may be useful in monitoring the therapeutic effect and recovery.

References

Jan 1, 1979·Journal of Immunological Methods·W Pernice, H H Sedlacek
Jan 1, 1978·Human Pathology·R T McCluskeyR B Colvin
Jan 1, 1973·Advances in Immunology·C G Cochrane, D Koffler
Jan 1, 1983·Transactions of the Royal Society of Tropical Medicine and Hygiene·M I DuarteV Amato Neto
Sep 1, 1981·Tubercle·J BrostoffL Rottoli
Apr 1, 1980·Thorax·N M JohnsonJ F Mowbray

❮ Previous
Next ❯

Citations

Oct 1, 1996·Zentralblatt für Veterinärmedizin. Reihe B. Journal of veterinary medicine. Series B·R LopezJ M Molleda
Sep 1, 1994·Transactions of the Royal Society of Tropical Medicine and Hygiene·J Q QuA Gilman-Sachs
Jan 1, 1994·Transactions of the Royal Society of Tropical Medicine and Hygiene·A A AzazyM L Chance
Jan 28, 2012·Journal of the American Society of Nephrology : JASN·Kerstin AmannJuergen Rech
Jul 23, 1998·Zentralblatt für Veterinärmedizin. Reihe B. Journal of veterinary medicine. Series B·J M MargaritoP J Ginel
Oct 1, 1991·Clinical Microbiology Reviews·S E Maddison

❮ Previous
Next ❯

Related Concepts

Related Feeds

Antibody Specificity

Antibodies produced by B cells are highly specific for antigen as a result of random gene recombination and somatic hypermutation and affinity maturation. As the main effector of the humoral immune system, antibodies can neutralize foreign cells. Find the latest research on antibody specificity here.