PMID: 70247Jul 1, 1977Paper

Detection of antigens of endogenous viruses of the C-type during mouse development

Biulleten' eksperimental'noĭ biologii i meditsiny
B P Bogovskii, O M Lezhneva

Abstract

Embryos of the 12th-20th day of gestation, newborn and adult AKR and BALB/c mice were investigated for the presence of mouse C-type virus major structural p30 protein (gs-1) and Gross leukemia virus type-specific antigen AGLV) by means of radioimmunodiffusion with test systems. The p30 protein was distinctly determined from the 12th day of intrauterine development in both mouse lines; it persisted in the embryo tissues until birth and was detectable also in the AKR and BALB/c mouse tissues from the first days of postnatal development and during the whole life. AGLV was not revealed in BALB/c and AKR embryos and in adult BALB/c mice; however it was found in the AKR newborn mice since the 1st-2nd day after birth. Basing on these data a conclusion was drawn that p30 protein and AGLV were expressed independently according to the radioimmuno-diffusion method sensitivity.

References

Jan 1, 1975·Cold Spring Harbor Symposia on Quantitative Biology·M StrandJ T August
Sep 1, 1970·Proceedings of the National Academy of Sciences of the United States of America·R J HuebnerR L Peters
Sep 15, 1970·International Journal of Cancer. Journal International Du Cancer·G I Abelev, D A Elgort
Feb 1, 1972·The Journal of Experimental Medicine·W P Rowe, T Pincus
Jan 1, 1974·Proceedings of the National Academy of Sciences of the United States of America·S K ChattopadhyayW P Rowe
Apr 1, 1968·Proceedings of the Society for Experimental Biology and Medicine·R Rugh, C Somogyi

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Citations

Feb 1, 1975·Biulleten' eksperimental'noĭ biologii i meditsiny·G E Rukavishnikova, A K Alekseeva
Nov 1, 1970·Biulleten' eksperimental'noĭ biologii i meditsiny·D K NovikovV I Novikova

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