Abstract
In pulmonate gastropods, the peptide, Ala-Pro-Gly-Trp-NH2 (APGWamide), appears to be located nearly exclusively in the neural circuitry controlling the male reproductive organs. This neuropeptide and related neuropeptides are also present and apparently bioactive in bivalve molluscs, although their physiological role in these latter animals is unknown. The present report uses immunohistochemistry to examine the distribution of APGWamide and/or related peptides within the tissues of the deep sea scallop, Placopecten magellanicus. Much of the APGWamide-like immunoreactivity (APGWa-LIR) was detected in the central nervous system (CNS) of both juvenile and adult scallops, where it was concentrated in the cerebral, pedal and parietovisceral ganglia, particularly in the cortex of ganglionic cells and their axons which extend into the central neuropilar region. APGWa-LIR was also detected in the nerves ramifying from these ganglia. In addition, strong APGWa-LIR was localized in what appeared to be axonal terminals within peripheral tissues including the striated adductor muscle, foot, gills, labial palps, lips, tentacles and gonads of the juvenile scallops. The presence of APGWa-LIR was also confirmed in the gonads of adults of both s...Continue Reading
References
Aug 12, 1977·Science·D A Price, M J Greenberg
May 15, 1992·Experientia·M O'Shea, R C Rayne
Jan 1, 1991·Comparative Biochemistry and Physiology. C, Comparative Pharmacology and Toxicology·H MinakataY Muneoka
Jan 1, 1983·Cell and Tissue Research·G B Stefano, R Martin
Aug 1, 1995·Cell and Tissue Research·C K Too, R P Croll
Citations
Apr 9, 2011·Invertebrate Neuroscience : in·Ronnarong PalasoonJittipan Chavadej
May 9, 2000·Brain Research·J HenryP Favrel
Oct 18, 2000·Peptides·M OhtaniY Muneoka
Nov 10, 2000·Peptides·E Oberdörster, P McClellan-Green
Jun 27, 2002·Peptides·M OhtaniS Aimoto
Sep 15, 2011·Invertebrate Neuroscience : in·P SirinupongJ van Minnen
May 22, 1998·General Pharmacology·A K Pani, R P Croll
Sep 2, 2008·Peptides·Steven J HussonLiliane Schoofs
Mar 22, 2008·Gene·Franck RodetPascal Favrel
Feb 20, 2008·Comparative Biochemistry and Physiology. Toxicology & Pharmacology : CBP·Imen KetataChristophe Minier
Feb 24, 2006·Molecular Reproduction and Development·Benoît BernayJoël Henry
Sep 10, 2005·Biochimica Et Biophysica Acta·Franck RodetPascal Favrel
Oct 23, 1997·The Journal of Comparative Neurology·X FanG T Nagle
Mar 27, 2018·ACS Chemical Neuroscience·Alexia T ScarosSébastien Baratte