Detection of Biofilm in Wounds as an Early Indicator for Risk for Tissue Infection and Wound Chronicity

Annals of Plastic Surgery
Krishna S Vyas, Lesley K Wong

Abstract

Wounds are dynamic environments in which dead tissue, exudate, and the bacterial bioburden interact in a complex manner among themselves and with the tissue of the host. Bacteria organize into biofilms, reducing their susceptibility to elimination by the host immune response and antimicrobials. Early detection of biofilms in wounds is crucial to successful chronic wound management; and although many techniques have developed to identify planktonic counterparts in viable wounds, few have been able to quickly and accurately identify bacterial biofilms. Future studies are needed to find means of identifying and monitoring biofilm colonization at the bedside to permit timely initiation of treatment. In this review, we examine some promising new technologies that hope to identify and quantify the process of biofilm formation in chronic wounds.

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Citations

Apr 14, 2016·Journal of Wound Care·L R Copeland-HalperinR Miraliakbari
Mar 14, 2020·British Journal of Nursing : BJN·Maria-Manuel AzevedoAcácio Rodrigues
Jan 8, 2016·Experimental Dermatology·Maria Luisa MangoniMichael Zasloff
Sep 14, 2017·Memórias do Instituto Oswaldo Cruz·Liliane de Fátima AntonioMaria Inês Fernandes Pimentel
Dec 14, 2017·Expert Review of Anti-infective Therapy·Jose Luis Del Pozo
Apr 21, 2018·Advances in Wound Care·Lene BayThomas Bjarnsholt
Dec 11, 2020·British Journal of Community Nursing·Maria AzevedoAcácio Rodrigues
Apr 16, 2021·Journal of Wound Care·Adam AstradaHiromi Sanada

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