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Detection of copy number variation from array intensity and sequencing read depth using a stepwise Bayesian model

BMC Bioinformatics

Nov 3, 2010

Zhengdong D Zhang, Mark Gerstein

Abstract

Copy number variants (CNVs) have been demonstrated to occur at a high frequency and are now widely believed to make a significant contribution to the phenotypic variation in human populations. Array-based comparative genomic hybridization (array-CGH) and newly developed read-depth appro...read more

Mentioned in this Paper

Glioblastoma Multiforme
CELSR1 gene
Microarray Analysis
Biologic Segmentation
DNA Copy Number Changes
Genome
Likelihood Functions
Iron in various other combinations
Burn brand of nitrofurazone
Array-Based Comparative Genomic Hybridization
Paper Details
References
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  • References31
  • Citations5
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Detection of copy number variation from array intensity and sequencing read depth using a stepwise Bayesian model

BMC Bioinformatics

Nov 3, 2010

Zhengdong D Zhang, Mark Gerstein

PMID: 21034510

DOI: 10.1186/1471-2105-11-539

Abstract

Copy number variants (CNVs) have been demonstrated to occur at a high frequency and are now widely believed to make a significant contribution to the phenotypic variation in human populations. Array-based comparative genomic hybridization (array-CGH) and newly developed read-depth appro...read more

Mentioned in this Paper

Glioblastoma Multiforme
CELSR1 gene
Microarray Analysis
Biologic Segmentation
DNA Copy Number Changes
Genome
Likelihood Functions
Iron in various other combinations
Burn brand of nitrofurazone
Array-Based Comparative Genomic Hybridization

Feeds With Similar Papers

Chromosomal Deletion

Chromosomal deletion includes the loss of a gene sequence of DNA. The location and the genes deleted determines the significance of this abnormality. There are many identified genetic disorders that are a result from chromosomal deletion including cri du chat and Prader-Willi syndrome. Discover the latest research on chromosomal deletions here.

Genomic Techniques

Recent developments in genomics and further development of advanced post-genomic technologies, it will be possible to apply a more holistic analysis to genomic analysis. Discover the latest research in Genomic Techniques.

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Paper Details
References
  • References31
  • Citations5
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  • References31
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