Detection of degenerative cartilage disease: comparison of high-resolution morphological MR and quantitative T2 mapping at 3.0 Tesla

Osteoarthritis and Cartilage
S ApprichSiegfried Trattnig

Abstract

The aim of the study was to investigate the association of T2 relaxation times of the knee with early degenerative cartilage changes. Furthermore the impact of unloading the knee on T2 values was evaluated. Forty-three patients with knee pain and an ICRS (International Cartilage Repair Society) cartilage defect grade <or=2 were examined with 3T magnetic resonance imaging (MRI). Morphological cartilage grading was based on high-resolution proton-density (PD), turbo-spin-echo (TSE) and three-dimensional (3D) isotropic True fast imaging with steady-state precession (FISP) images of slices covering the cartilage layer above the posterior horn of the meniscus. T2 maps were calculated from a multi-echo, spin-echo (MESE) sequence, performed at the beginning and at the end of the scan (time interval 40 min). Influence of cartilage defect grading on deep, superficial, and global T2 values as well as on T2 values for zonal variation was assessed using analysis of variance (ANOVA) and Spearman rank correlation test. Differences among both T2 measurements were compared using paired t-test. Global and superficial T2 values significantly increased with cartilage defect grade regardless of the time elapsed from unloading (global T2: ICRS grad...Continue Reading

References

Oct 6, 1997·AJR. American Journal of Roentgenology·J D RubensteinR M Henkelman
Nov 14, 1997·Radiology·B J DardzinskiM B Smith
May 9, 2000·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·M T NieminenJ S Jurvelin
Oct 21, 2000·Investigative Radiology·M HuberF Lintner
Jul 4, 2001·Journal of Magnetic Resonance Imaging : JMRI·H E SmithM B Smith
Dec 18, 2001·Seminars in Musculoskeletal Radiology·M L GrayY Xia
Feb 12, 2002·The Journal of Bone and Joint Surgery. British Volume·B H BrismarO Svensson
Nov 20, 2004·Radiology·Timothy J MosherMichael B Smith
Jan 12, 2005·Seminars in Musculoskeletal Radiology·Timothy J Mosher, Bernard J Dardzinski
May 24, 2006·Osteoarthritis and Cartilage·Garry E GoldTimothy Mosher
Aug 12, 2006·Osteoarthritis and Cartilage·D Burstein, M L Gray
Nov 1, 2006·NMR in Biomedicine·Felix EcksteinThomas M Link
Nov 10, 2006·European Radiology·Thomas M LinkKlaus Woertler
Oct 31, 2007·Archives of Orthopaedic and Trauma Surgery·L V von EngelhardtF von Falkenhausen
Jun 27, 2008·Journal of Magnetic Resonance Imaging : JMRI·Takashi NishiiHideki Yoshikawa
Feb 21, 2009·The Journal of Bone and Joint Surgery. American Volume·Deborah Burstein

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Citations

May 18, 2013·Transplantation·Lluis OrozcoJavier García-Sancho
Nov 9, 2012·Journal of the Royal Society, Interface·Deva D Chan, Corey P Neu
Sep 10, 2013·International Orthopaedics·Ulrich KollerSiegfried Trattnig
Oct 31, 2013·Knee Surgery, Sports Traumatology, Arthroscopy : Official Journal of the ESSKA·Rachel K SurowiecCharles P Ho
Apr 10, 2014·European Journal of Radiology·Fernando Ruiz SantiagoMaría Del Mar Castellano García
Dec 3, 2014·Magnetic Resonance Imaging Clinics of North America·Richard Kijowski, Rajeev Chaudhary
Jun 15, 2011·Magnetic Resonance Imaging Clinics of North America·Jung-Ah Choi, Garry E Gold
Nov 19, 2011·Veterinary Radiology & Ultrasound : the Official Journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association·Katja L WuchererMichael G Conzemius
Feb 13, 2013·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Petros MartirosianMichael Deimling
Oct 12, 2013·Journal of Magnetic Resonance Imaging : JMRI·Fang LiuRichard Kijowski
Oct 4, 2014·Osteoarthritis and Cartilage·C RehnitzM-A Weber
Oct 4, 2014·Osteoarthritis and Cartilage·R KijowskiR B Frobell
May 12, 2015·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Fang LiuAlexey Samsonov
Sep 23, 2014·Journal of Magnetic Resonance Imaging : JMRI·Stephen J MatzatGarry E Gold
May 23, 2015·Investigative Radiology·Reto SutterChristian W A Pfirrmann
Apr 22, 2015·Arthroscopy : the Journal of Arthroscopic & Related Surgery : Official Publication of the Arthroscopy Association of North America and the International Arthroscopy Association·Fernando P FerroMarc J Philippon
Jul 7, 2016·Journal of Magnetic Resonance Imaging : JMRI·Christoph RehnitzMarc-André Weber
Jun 8, 2017·AJR. American Journal of Roentgenology·Guillaume LefebvreAnne Cotten
Nov 30, 2010·Physics in Medicine and Biology·Paola CoanJuergen Mollenhauer
Dec 27, 2019·Journal of Cellular and Molecular Medicine·Pei MaQi Hou
May 2, 2019·BMC Musculoskeletal Disorders·Hayden F AtkinsonR Terry Thompson
Oct 1, 2019·The Journal of International Medical Research·Leiyu QiuMichael G Baraga
Apr 22, 2018·Skeletal Radiology·Domenico AlbanoMassimo Galia
May 24, 2018·European Radiology·Jan RechsteinerAnna Hirschmann
Jan 23, 2021·Journal of Biomechanics·Matthew M GrondinCorinne R Henak

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