PMID: 6161498Sep 1, 1980Paper

Detection of early kidney damage in workers exposed to lead, mercury, and cadmium (author's transl)

Zentralblatt für Bakteriologie, Mikrobiologie und Hygiene. Serie B, Umwelthygiene, Krankenhaushygiene, Arbeitshygiene, präventive Medizin
K H SchallerR Schiele

Abstract

Our study was performed to evaluate potential adverse effects on the kidney caused by an occupational exposure to cadmium, lead, and mercury, respectively. We examined 81 individuals of a Zn-Cd-plant and of a Ni-Cd-battery factory, occupationally exposed to cadmium. In a chemical company, synthesizing mercury-compounds, we analyzed 23 exposed workers. The 21 persons with an exposure to lead were employed in a secondary lead smelting plant. To evaluate the degree of the occupational exposure we analyzed the concentrations of the heavy metals in blood and urine samples. As indicators of an adverse effect on the kidney the renal elimination of specific proteins was determined. The analysis of proteins with a higher molecular weight, such as albumine and acid alpha 1-glycoproteine, was performed using a new developed laser nephelometric method. Patterns of renal eliminated proteins with a lower molecular weight were characterized applying radio immunological determination of beta 2-microglobuline. The results found in workers exposed to cadmium verified previous studies. The occurrence of a characteristic beta 2-microglobulinuria takes place after a sufficient long period of exposure. In addition to this, cadmium exposed workers ha...Continue Reading

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Arhiv za higijenu rada i toksikologiju
N Restek-SamarzijaM Samarzija
Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases
Wei-jun GuoHong-ping Deng
Journal of Occupational Medicine. : Official Publication of the Industrial Medical Association
J P BuchetR Lauwerys
International Archives of Occupational and Environmental Health
M D StonardG T Steel
© 2021 Meta ULC. All rights reserved