Detection of gonadal carcinoma in situ in childhood and implications for management

The Australian and New Zealand Journal of Surgery
R A MacMahon, L J Cussen


Cells with the characteristic features of carcinoma in situ (CIS) were detected in histological sections of the gonads of three of seven children with clinical syndromes associated with a high risk of gonadal neoplasia. It is suggested that early detection of these cells may be useful in resolving problems of management, including gonadectomy and decisions about sex of rearing. Early detection of CIS cells may have a place in the management of the undescended testis.


May 20, 2003·APMIS : Acta Pathologica, Microbiologica, Et Immunologica Scandinavica·E Rajpert-De MeytsNiels E Skakkebaek


Mar 1, 1979·The Journal of Urology·S A Brosman
Feb 11, 1976·American Journal of Obstetrics and Gynecology·M ManuelH W Jones
Feb 1, 1987·International Journal of Andrology·H von der MaaseNiels E Skakkebaek
Mar 1, 1985·The Journal of Pediatrics·J MüllerK E Petersen
Sep 9, 1972·Lancet·Niels E Skakkebaek
Mar 1, 1981·International Journal of Andrology·Jørgen G Berthelsen, Niels E Skakkebaek

Related Concepts

Undescended Testis (Body Structure)
Ovarian Neoplasm
Gonadal Agenesis
Neoplastic Disease
Gonadal Structure

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