Abstract
Helicobacter pylori (H pylori) infection has been suggested to be a risk factor for gastric carcinogenesis. However, those previous studies have been concerned with advanced cancer cases. To the authors' knowledge, no detailed investigation on the prevalence of H pylori in early stage gastric cancer tissue has been performed. The relationship between early stage gastric cancer and the prevalence of H pylori was studied by a immunohistochemical staining analysis. Sixty-eight patients who were endoscopically and surgically diagnosed as having early stage gastric cancer were enrolled in this study. All tissue specimens were obtained from patients by endoscopic biopsy, and were classified histopathologically as the intestinal-type of early stage gastric cancer in 34 patients (male-to-female ratio, 28:6; age, 64 +/- 11 years) and the diffuse-type of early stage gastric cancer (male-to-female ratio, 23:11; age, 57 +/- 14 years) in the other 34 patients. The amount of H pylori in tissue samples was graded from 0 (no characteristic bacteria) to 3 (numerous bacteria) using the fluorescent microscopic and an immunohistochemical technique. Twenty-nine of the 34 cases of the intestinal-type of gastric cancer had H pylori infection, as comp...Continue Reading
References
Aug 1, 1992·Gut·A WeeM Teh
Mar 1, 1992·Gastroenterology·M AsakaD Y Graham
Dec 1, 1991·Journal of Clinical Gastroenterology·T OhkusaN Yamamoto
Jan 1, 1991·Scandinavian Journal of Gastroenterology. Supplement·S Recavarren-ArceW M Spira
Oct 17, 1991·The New England Journal of Medicine·J ParsonnetR K Sibley
Oct 17, 1991·The New England Journal of Medicine·A NomuraM J Blaser
Oct 17, 1991·The New England Journal of Medicine·P Correa
Mar 24, 1990·Lancet·N ScottP Quirke
May 1, 1991·Journal of the National Cancer Institute·J ParsonnetY Chang
Jun 1, 1991·BMJ : British Medical Journal·D FormanF Sitas
Dec 1, 1990·Histopathology·R J LoffeldJ W Arends
Oct 15, 1990·International Journal of Cancer. Journal International Du Cancer·D FormanJ Chen
Dec 15, 1990·Cancer·P CorreaH Portilla
Jan 4, 1986·Lancet·L L WaltersG Paull
Feb 15, 1988·International Journal of Cancer. Journal International Du Cancer·D M ParkinC S Muir
Jan 1, 1986·Epidemiologic Reviews·C P HowsonE L Wynder
Jan 1, 1972·Journal of Clinical Pathology·R WhiteheadM W Gear
Jun 16, 1984·Lancet·B J Marshall, J R Warren
Apr 1, 1981·The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society·S M HsuH Fanger
Jun 1, 1981·American Journal of Clinical Pathology·S M HsuH Fanger
Oct 1, 1984·British Medical Bulletin·D Coggon, E D Acheson
Apr 1, 1984·British Journal of Cancer·P SipponenM Siurala
Jun 1, 1994·Cancer·M AsakaD Y Graham
Jan 15, 1993·Cancer·J GuarnerD Halperin
Sep 1, 1955·British Journal of Cancer·B C MORSON
Jan 1, 1965·Acta Pathologica Et Microbiologica Scandinavica·P LAUREN
Citations
Oct 1, 1996·Glycoconjugate Journal·H KawasakiJ E Silbert
Jan 1, 1997·Biomedicine & Pharmacotherapy = Biomédecine & Pharmacothérapie·T ShibataE C Gabazza
Aug 10, 2000·Histopathology·Y KoshidaI Okayasu
Feb 24, 2001·Journal of Gastroenterology and Hepatology·S FukudaY Yoshida
Feb 24, 2001·Journal of Gastroenterology and Hepatology·M KurosawaF Kobayashi
Feb 15, 2001·Annals of Surgery·C N ChenK J Chang
Apr 1, 1996·Journal of Clinical Gastroenterology·P A TestoniR Scelsi
Oct 18, 2000·Journal of Clinical Gastroenterology·Y TokunagaK Ohsumi
Mar 19, 2003·Journal of Clinical Gastroenterology·Kunio TakeuchiHiroyuki Kuwano
Jun 1, 1997·Journal of Gastroenterology and Hepatology·M S WuJ T Lin
Jan 8, 1998·Helicobacter·H Y KimD Y Graham
Nov 22, 1997·APMIS : Acta Pathologica, Microbiologica, Et Immunologica Scandinavica·S HolckL P Andersen
Mar 20, 1998·Gut·K IsekiS Ishiguro
Dec 22, 2011·Pathology·Suw Young LySeung Kyu Chun
Jun 3, 1998·Gastroenterology·J Q HuangR H Hunt
Aug 28, 1998·Gastroenterology·T WatanabeM Nakao
Aug 1, 1997·Pathology·V MisraS C Gupta
Aug 18, 2001·Japanese Journal of Cancer Research : Gann·N FujiokaS Tsugane
Jun 19, 2002·Arquivos De Gastroenterologia·L P PereiraH P Soares
May 25, 2007·The American Journal of Gastroenterology·Changcheng WangRichard H Hunt
Aug 10, 2013·European Journal of Gastroenterology & Hepatology·Joana I MatosMário Dinis-Ribeiro