Detection of hepatocellular carcinoma: gadoxetic acid-enhanced 3-dimensional magnetic resonance imaging versus multi-detector row computed tomography

Journal of Computer Assisted Tomography
Young Kon KimHee Chul Yu

Abstract

The aim of this study was to compare the diagnostic accuracy and sensitivity of gadoxetic acid-enhanced magnetic resonance imaging (MRI) with multi-detector row computed tomography (MDCT) for the detection of hepatocellular carcinomas (HCCs). Sixty-two patients (81 HCCs) who underwent MDCT and gadoxetic acid-enhanced MRI using a 3-dimensional volumetric interpolated technique with a mean interval of 7 days (range, 3-11 days) were included in this study. Two observers reached a consensus on 2 sets of images: the gadoxetic acid set (unenhanced, early dynamic, 10-minute, and 20-minute hepatocyte phase images) and the 3-phase MDCT. Diagnostic accuracy and sensitivity were evaluated using the alternative-free response receiver operating characteristic method. There was a trend toward increased area under the receiver operating characteristic curve (Az value) for the gadoxetic acid set (0.963) as compared with the MDCT (0.930), but no significant difference was found (P = 0.41). Sensitivity of the gadoxetic acid set (91.4%) was better than that of the MDCT (71.6%; P = 0.0001). There were 12 lesions that showed only arterial hypervascularization on MDCT but showed arterial hypervascularization and delayed hypointensity on the gadoxeti...Continue Reading

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Citations

Mar 16, 2012·Cancer Imaging : the Official Publication of the International Cancer Imaging Society·Huedayi KorkusuzThomas J Vogl
Oct 14, 2011·International Journal of Hepatology·Jendana ChanyaputhipongPierce K H Chow
Oct 19, 2011·International Journal of Hepatology·Cher Heng TanChoon Hua Thng
Feb 9, 2016·Diagnostics·Christina SchramlKonstantin Nikolaou
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Jan 24, 2015·Abdominal Imaging·Ryan B SchwopeDaniel J A Margolis
Feb 27, 2020·Magnetic Resonance in Medical Sciences : MRMS : an Official Journal of Japan Society of Magnetic Resonance in Medicine·Shintaro IchikawaTomoaki Ichikawa
May 3, 2012·Veterinary Radiology & Ultrasound : the Official Journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association·Daisuke YonetomiTetsuya Nakade
May 21, 2014·Journal of Magnetic Resonance Imaging : JMRI·Ju Hyun ShimHan Chu Lee
Nov 1, 2013·Magnetic Resonance in Medical Sciences : MRMS : an Official Journal of Japan Society of Magnetic Resonance in Medicine·Dai JoishiSachio Kuribayashi

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