Detection of hepatocellular carcinoma in patients with cirrhosis: MR imaging versus angiographically assisted helical CT

AJR. American Journal of Roentgenology
M KanematsuH Nakamura


The purpose of our study was to compare the combination of conventional spin-echo, phase-shift gradient-recalled echo (GRE), and triple-phasic dynamic GRE MR imaging with the combination of helical CT hepatic arteriography (CTA) and CT performed during arterial portography (CTAP) in the preoperative detection of hepatocellular carcinoma (HCC). Thirty-seven patients with cirrhosis underwent MR imaging and angiographically assisted CT imaging. Paired T1- and T2-weighted spin-echo images, paired in-phase and out-of-phase GRE images, triple-phasic dynamic GRE images, the combined MR images, and the paired CTA and CTAP images were retrospectively and independently reviewed by three radiologists. Image review was done on a segment-by-segment basis. Of the 280 liver segments, 58 segments contained 79 HCCs that were 0.5-8.0 cm (mean, 2.0 cm) in diameter. The diagnostic value of each pair of images was rated by means of receiver operating characteristic curve analysis. The diagnostic accuracy of combined CTA and CTAP (mean area under the receiver operating characteristic curve [Az] = 0.94) was significantly better than that of spin-echo (Az = 0.86, p < .0001), phase-shift GRE (Az = 0.83, p < .0001), dynamic GRE (Az = 0.85, p < .0001), a...Continue Reading


Jul 24, 2002·Gastroenterology Clinics of North America·Marie Ann Bailey, Elizabeth M Brunt
Aug 7, 2002·Internal Medicine Journal·G W McCaughanS I Strasser
Feb 6, 2008·Cancer Imaging : the Official Publication of the International Cancer Imaging Society·C H Thng, Y T Kuo
Jan 6, 2000·Postgraduate Medical Journal·S Badvie
Apr 25, 2006·AJR. American Journal of Roentgenology·Khaled M ElsayesJeffrey J Brown
Feb 24, 2009·AJR. American Journal of Roentgenology·Hidenori ToyodaYasuhiro Sone
Jan 25, 2011·AJR. American Journal of Roentgenology·Masanori TakahashiOsamu Yokosuka
Jun 22, 2001·AJR. American Journal of Roentgenology·T YamagamiT Nishimura
Apr 13, 2011·World Journal of Gastroenterology : WJG·Janine RennertNiels Zorger
Aug 25, 2004·The British Journal of Radiology·K T T FungA K Burroughs
Feb 6, 2010·Journal of Vascular and Interventional Radiology : JVIR·Alessia TognoliniNishita Kothary
Apr 5, 2014·Hepatology Research : the Official Journal of the Japan Society of Hepatology·Kazuhiro KatayamaKatsuyuki Nakanishi
Aug 21, 2003·Journal of Nippon Medical School = Nippon Ika Daigaku Zasshi·Yutaka AbeTatsuo Kumazaki
Sep 3, 2002·Journal of Magnetic Resonance Imaging : JMRI·Hiroshi YoshiokaYuji Itai
Dec 11, 2002·Liver Transplantation : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society·Glenn A KrinskyA S Goldenberg
Jul 25, 2007·Hepatology Research : the Official Journal of the Japan Society of Hepatology·Yasuharu ImaiHironobu Nakamura
Nov 20, 2002·Journal of Computer Assisted Tomography·Masatoshi HoriHironobu Nakamura
Jul 4, 2015·World Journal of Hepatology·Magdy Hamed Attwa, Shahira Aly El-Etreby

Related Concepts

Liver Carcinoma
Fibrosis, Liver
Malignant Neoplasm of Liver
Magnetization Transfer Contrast Imaging
Retrospective Studies
Receiver Operating Characteristic
Tomography, X-Ray Computerized Axial

Related Feeds

Carcinoma, Hepatocellular

Hepatocellular Carcinoma is a malignant cancer in liver epithelial cells. Discover the latest research on Hepatocellular Carcinoma here.