Detection of hepatopulmonary syndrome in patients with liver cirrhosis using 3D contrast echocardiography

Arab Journal of Gastroenterology : the Official Publication of the Pan-Arab Association of Gastroenterology
Rania GaberManal Hamisa

Abstract

Hepatopulmonary syndrome (HPS) is characterised by the triad of advanced liver disease, arterial hypoxaemia and intrapulmonary vascular dilatation (IPVD). The present study aimed to evaluate HPS in patients with liver cirrhosis and the role of three-dimensional (3D) contrast echocardiography in the detection of this syndrome. A total of 78 chronic liver disease patients aged 42 ± 11 years fulfilled the criteria for this study and were subjected to clinical examination, laboratory investigations, arterial blood gases measurement, pulmonary function tests, upper gastrointestinal endoscopy, 3D contrast echocardiography and computed tomography (CT) pulmonary angiography. According to 3D contrast echocardiography results, we divided the patients into a positive group (n=26) in which patients showed a delayed appearance of contrast in left heart chambers and a negative group (n=52). Among 26 patients of the positive group, nine had hypoxaemia (partial pressure of oxygen (PaO(2)) <70 mm Hg) and were diagnosed as having hepatopulmonary syndrome (HPS), the other 17 who had shown echocardiographic evidence of IPVDs but without hypoxaemia were diagnosed as having sub-clinical HPS. This study showed significant correlation between positive...Continue Reading

References

Jan 1, 1991·Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography·J J NemecE E Salcedo
May 1, 1988·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·P GinèsF Rivera
May 1, 1994·Revista clínica española·E Asín Cardiel, M Jiménez Mena
May 1, 1997·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·M J Krowka
May 29, 2000·Journal of Gastroenterology and Hepatology·B K DeA K Maity
Sep 26, 2000·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·M B Fallon, G A Abrams
Dec 26, 2001·Liver Transplantation : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society·C E AvendanoA Reuben
Apr 20, 2002·Liver Transplantation : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society·Peter StarkelDavid Mutimer
Nov 18, 2003·Heart·J TimperleyH Becher
Nov 22, 2008·Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography·Ilaria LenciRichard Steeds
Dec 17, 2009·São Paulo Medical Journal = Revista Paulista De Medicina·Liana Gonçalves de Macêdo, Edmundo Pessoa de Almeida Lopes

❮ Previous
Next ❯

Citations

Mar 4, 2015·Digestive Diseases and Sciences·Yong Lv, Daiming Fan

❮ Previous
Next ❯

Related Concepts