Detection of Human Papilloma Virus (Type 16) among HIV-Positive Women in Ogbomoso, South-Western Nigeria

Journal of Immunoassay & Immunochemistry
Oladipo Elijah KolawoleE A Adekeye

Abstract

Human papilloma virus (HPV) is a common sexually transmitted virus which infects the cutaneous and mucosal epithelium. HPV Type 16 is one of the viruses that causes cervical cancer and immunocompromised individuals are at high risk of different co-infections. Women living with Human Immunodeficiency Virus (HIV) have greater risk to the virus due to their impaired immunity. This study aimed at determining the seroprevalence of HPV IgM (Type 16) among HIV-infected women in Ogbomoso. The blood sample of 180 consenting subjects were obtained and their sera subjected to serological assay using Enzyme Linked Immunosorbent Assay. Samples were collected over a period of 6 months (July-December 2014). The mean age and mean CD4+ count of the subjects was 38.22 ± 0.79 years and 392.80 ± 20.98 cells/μL, respectively. Out of 180 subjects tested, 18 (10%; 95% confidence interval) were positive for HPV Type 16 IgM. HPV Type 16 IgM was highest among the age group 31-45 (61.11%), traders (38.89%), >500 CD4/μL (33.33%). The seroprevalence using logistic regression at P < 0.05 shows there is a significant difference between the age and CD4 (+) cell count. The result provides evidence that HPV Type 16 is present among HIV-infected women in Ogbomos...Continue Reading

References

Nov 14, 1997·The New England Journal of Medicine·X W SunT C Wright
Feb 12, 1998·The New England Journal of Medicine·G Y HoR D Burk
Jan 26, 2002·American Journal of Obstetrics and Gynecology·Denise J JamiesonUNKNOWN HIV Epidemiology Research Study (HERS) Group
Jul 17, 2003·Journal of the National Cancer Institute·Howard D StricklerRobert D Burk
Aug 5, 2003·Sexually Transmitted Diseases·Elena MatosUNKNOWN Proyecto Concordia Collaborative Group
Oct 2, 2003·Sexually Transmitted Diseases·Silvia de SanjoseF Xavier Bosch
Feb 5, 2004·British Journal of Cancer·J O ThomasS Franceschi
Jun 9, 2004·Virology·Ethel-Michele de VilliersHarald zur Hausen
Apr 21, 2005·Journal of the National Cancer Institute·Howard D StricklerJoel M Palefsky
Nov 23, 2006·AIDS·Gary M CliffordUNKNOWN HPV and HIV Study Group
Sep 15, 2007·Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology·Gary M CliffordSilvia Franceschi
Oct 23, 2008·European Journal of Cancer Prevention : the Official Journal of the European Cancer Prevention Organisation (ECP)·Hugo De VuystJennifer S Smith
Mar 9, 2010·Virology·Hans-Ulrich BernardEthel-Michele de Villiers
Sep 10, 2010·Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology·Salvatore VaccarellaUNKNOWN IARC HPV Prevalence Surveys Study Group
Dec 6, 2011·BMC Infectious Diseases·Nienke J VeldhuijzenJanneke H H M van de Wijgert
Feb 6, 2016·MMWR. Surveillance Summaries : Morbidity and Mortality Weekly Report. Surveillance Summaries·Walter W WilliamsCarolyn B Bridges

❮ Previous
Next ❯

Methods Mentioned

BETA
Enzyme Linked Immunosorbent Assay
ELISA

Software Mentioned

SPSS

Related Concepts

Related Feeds

HIV/AIDS-Related Malignancies

HIV/AIDS infection increases the risk of non-communicable diseases common in the aged including HIV/AIDS-related malignancies. Discover the latest research in HIV/AIDS-related malignancies.

Cancer Vaccines

Cancer vaccines are vaccines that either treat existing cancer or prevent development of a cancer.