PMID: 8943745Oct 1, 1996Paper

Detection of integrated high risk human papillomavirus in adenoid cystic carcinoma of the uterine cervix

Journal of Clinical Pathology
W GraysonK Cooper

Abstract

To investigate the role of human papillomavirus (HPV) in adenoid cystic carcinoma of the uterine cervix. Eleven archival, paraffin wax embedded specimens were analysed by non-isotopic in situ hybridisation (NISH) for HPV types 6, 11, 16, 18, 31, and 33 using digoxigenin labelled probes. The polymerase chain reaction (PCR) was carried out on each of the cases using consensus primers to HPV. A total of eight adenoid cystic carcinomas harboured the HPV genome by NISH, of which five were PCR positive. Integrated HPV 16 DNA was demonstrated in seven of the eight NISH positive cases. One adenoid cystic carcinoma showed integrated HPV 31. HPV DNA was not detected in the three remaining cases. Integrated high risk HPV genome, in particular type 16, is associated with this uncommon type of primary cervical cancer.

References

Feb 1, 1992·Human Pathology·M H StolerT R Broker
May 1, 1992·Journal of Clinical Pathology·K CooperJ O McGee
May 1, 1992·Journal of Clinical Pathology·C S HerringtonJ O McGee
Jan 1, 1992·International Journal of Gynecological Pathology : Official Journal of the International Society of Gynecological Pathologists·J Albores-SaavedraE Gould
Apr 1, 1990·Journal of Clinical Pathology·F Chang
Feb 1, 1988·The American Journal of Surgical Pathology·J A Ferry, R E Scully
Oct 1, 1985·Gynecologic Oncology·A G MusaS A Coleman
Oct 1, 1974·American Journal of Surgery·R H SpiroE W Strong
Feb 1, 1994·Human Pathology·K Cooper

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Citations

Oct 14, 2004·European Radiology·Ayumi KakuIsao Miyakawa
Jul 2, 2005·International Journal of Clinical Oncology·Masakazu NishidaKenji Kashima
Dec 14, 2011·Modern Pathology : an Official Journal of the United States and Canadian Academy of Pathology, Inc·Jennifer M BolandDavid J Schembri-Wismayer
Sep 28, 2002·International Journal of Gynecological Pathology : Official Journal of the International Society of Gynecological Pathologists·Michael Wells, Laurence J R Brown
Aug 27, 2002·Advances in Anatomic Pathology·Wayne Grayson, Kumarasen Cooper
Aug 17, 2006·Diagnostic Pathology·Michael J Russell, Oluwole Fadare
May 17, 2011·Annales de dermatologie et de vénéréologie·H DroussiS Boukind
Mar 1, 2011·Surgical Pathology Clinics·Kay J Park
Aug 5, 2008·Annales de pathologie·Marie-Laure Quintyn-RantyMarie-Bernadette Delisle
Sep 6, 2005·Gynecologic Oncology·Shlomo A KoyfmanMasoud Azodi
Sep 10, 2005·Best Practice & Research. Clinical Obstetrics & Gynaecology·A J Tiltman
Feb 19, 2000·The American Journal of Surgical Pathology·W Grayson, K Cooper
Jun 1, 1997·Molecular Pathology : MP·K CooperL Taylor
Feb 4, 2012·The American Journal of Surgical Pathology·Stefan KraftJeffrey F Krane
Dec 10, 2015·The American Journal of Surgical Pathology·Deyin XingBrigitte M Ronnett
Apr 30, 2020·Pathology, Research and Practice·Gatske M Nieuwenhuyzen-de BoerMieke R Van Bockstal
Jun 25, 2004·Archives of Pathology & Laboratory Medicine·Haytham H DimashkiehMary B Casey

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