Detection of Leptospira interrogans in Hedgehogs from Central China.

Vector Borne and Zoonotic Diseases
Xiao-Juan MaXue-Jie Yu

Abstract

Background: Leptospira is the causative agent of leptospirosis, a zoonotic disease of global importance. To have a better understanding on the host species of Leptospira, we investigated the prevalence of Leptospira species in hedgehogs in Central China. Materials and Methods: Hedgehogs were captured in Hubei Province, China in May and October, 2018. Total DNA was extracted from the kidney tissues of hedgehogs for determining the Leptospira species by PCR amplification of the rrs2, secY, and flaB genes with genus-specific primers. Results: PCR amplification indicated that the positive rate of hedgehogs to the rrs2, secY, and flaB genes were 19.5% (8/41), 12.2% (5/41), and 9.8% (4/41), respectively. The homology of the partial sequence of rrs2, secY, and flaB genes were 99.0-100% among the Leptospira strains from hedgehogs. Phylogenetic analysis revealed that Leptospira species detected in this study clustered together with Leptospira interrogans. Conclusions: We detected L. interrogans from hedgehogs in Central China, suggesting hedgehogs are the hosts of L. interrogans.

References

Jan 1, 1977·New Zealand Veterinary Journal·R E Brockie, D G Till
Jan 1, 1989·Journal of Comparative Pathology·S K MajeedJ E Cooper
Feb 9, 1985·British Medical Journal·S Waitkins
Nov 1, 1958·The Journal of Infectious Diseases·J VAN DER HOEDEN
Jun 18, 1960·Lancet·J C BROOM, J D COGHLAN
Jan 1, 1964·Pathologia et microbiologia·B BABUDIERI, R FARINA
Dec 4, 2003·The Lancet Infectious Diseases·Ajay R BhartiUNKNOWN Peru-United States Leptospirosis Consortium
Feb 4, 2006·Journal of Wildlife Diseases·T E CoxL K-P Leung
Aug 25, 2009·Transactions of the Royal Society of Tropical Medicine and Hygiene·Mirjana Balen TopicNenad Turk
Sep 8, 2009·BMC Infectious Diseases·Ann Florence B VictorianoBen Adler
Sep 17, 2009·Nature Reviews. Microbiology·Albert I KoMathieu Picardeau
Dec 14, 2011·Microbes and Infection·Chenglin ZhangJie Yan
Jun 6, 2012·The American Journal of Tropical Medicine and Hygiene·Svilena IvanovaSerge Morand
Sep 29, 2012·Emerging Infectious Diseases·Erwan LagadecKoussay Dellagi
Jul 26, 2014·Current Opinion in Infectious Diseases·Weilin HuJie Yan
Mar 21, 2015·Infection, Genetics and Evolution : Journal of Molecular Epidemiology and Evolutionary Genetics in Infectious Diseases·Hirohito OgawaHirofumi Sawa
Sep 18, 2015·PLoS Neglected Tropical Diseases·Mwanajaa Abdalla MwachuiJan Hattendorf
Oct 3, 2015·PLoS Neglected Tropical Diseases·Paul R TorgersonBernadette Abela-Ridder
Nov 13, 2015·PLoS Pathogens·Muriel DietrichWanda Markotter
May 19, 2018·Emerging Infectious Diseases·Hui-Ju HanXue-Jie Yu

❮ Previous
Next ❯

Citations

Apr 18, 2020·Vector Borne and Zoonotic Diseases·Xiao-Qing GongXue-Jie Yu
May 1, 2021·Animals : an Open Access Journal From MDPI·Ivana PireddaValentina Chisu
Jul 3, 2021·Animals : an Open Access Journal From MDPI·Jakub J RuszkowskiMałgorzata Pomorska-Mól

❮ Previous
Next ❯

Methods Mentioned

BETA
PCR
PCRs
electrophoresis

Software Mentioned

MEGA
ClustalW
BLAST

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

© 2021 Meta ULC. All rights reserved