Detection of melamine in milk by surface-enhanced Raman spectroscopy coupled with magnetic and Raman-labeled nanoparticles

Analytical and Bioanalytical Chemistry
Nazife Nur YazganUğur Tamer

Abstract

A new method based on surface-enhanced Raman spectroscopy (SERS) has been developed for sensitive and rapid detection of melamine. Spherical magnetic-core gold-shell nanoparticles (AuNPs) and rod-shaped gold nanoparticles (nanorods) labeled with a Raman-active compound were used to form a complex with the melamine molecules. 5,5'-Dithiobis(2-nitrobenzoic acid) was used as Raman-active compound because it is readily adsorbed by a gold nanoparticle surface forming a self-assembled monolayer (SAM) and has strong Raman scattering at 1330 cm(-1), because of the symmetric NO(2) stretch. The calibration curve was obtained by plotting Raman band area at 1330 cm(-1) against melamine concentration. A linear relationship was obtained with a high determination coefficient (R(2)=0.997). The method was validated for linearity, sensitivity, precision (intra-day and inter-day repeatability), and recovery. In the model system, the limits of detection (LOD) and quantification (LOQ) were 0.38 and 1.27 mg L(-1), respectively. For melamine-spiked milk samples, LOD and LOQ values were 0.39 mg L(-1) and 1.30 mg L(-1), respectively. Intra and inter-day precision were 3.73 and 4.94 %, respectively. This method was applied to samples of skimmed milk tha...Continue Reading

References

Oct 1, 2005·Analytical Chemistry·Jeremy D DriskellJulia F Ridpath
May 2, 2007·Journal of the American Chemical Society·Gary BraunNorbert Reich
Sep 8, 2007·Journal of Veterinary Diagnostic Investigation : Official Publication of the American Association of Veterinary Laboratory Diagnosticians, Inc·Cathy A BrownScott A Brown
Nov 14, 2007·Journal of Veterinary Diagnostic Investigation : Official Publication of the American Association of Veterinary Laboratory Diagnosticians, Inc·Birgit PuschnerPatricia A Pesavento
Apr 9, 2008·Journal of Food Protection·Eric A E Garber
Sep 4, 2008·Journal of the American Veterinary Medical Association·Rachel E CiancioloLaurie M Serfilippi
Oct 31, 2008·Lancet·E Y Y ChanC W Chan
Dec 26, 2008·The New England Journal of Medicine·Julie R Ingelfinger
Dec 15, 2010·Biosensors & Bioelectronics·Zhijiao WuZhuobin Yuan
May 17, 2011·Analytical and Bioanalytical Chemistry·Tingting LouLingxin Chen

❮ Previous
Next ❯

Citations

Jan 1, 2013·Chemical Reviews·Yunqing WangLingxin Chen
Jun 19, 2013·Food Additives & Contaminants. Part A, Chemistry, Analysis, Control, Exposure & Risk Assessment·Limin YangSuyi Zhang
Nov 1, 2013·Journal of Environmental Science and Health. Part C, Environmental Carcinogenesis & Ecotoxicology Reviews·C Y Chu, C C Wang
Apr 27, 2013·Journal of Proteomics·Ganesh Kumar AgrawalRandeep Rakwal
Aug 30, 2016·Journal of Food Science and Technology·Guluzar Gorkem BuyukgozIsmail Hakki Boyaci
Apr 15, 2016·Critical Reviews in Analytical Chemistry·Yang LuShuo Wang
Oct 11, 2016·Analytical and Bioanalytical Chemistry·Yesim Somay SelbesUgur Tamer
Aug 24, 2016·Chemphyschem : a European Journal of Chemical Physics and Physical Chemistry·Stefano ScaramuzzaVincenzo Amendola
Mar 29, 2014·Chemphyschem : a European Journal of Chemical Physics and Physical Chemistry·Limiao ChenGuanzhou Qiu
Jan 31, 2019·Scientific Reports·Farai GombedzaBidhan C Bandyopadhyay
Oct 11, 2013·Physical Chemistry Chemical Physics : PCCP·Scott G HarrounRobert D Singer
Dec 17, 2020·Comprehensive Reviews in Food Science and Food Safety·Yiqun HuangBarbara A Rasco

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.