Detection of Mycobacterium tuberculosis genotypic groups by a duplex real-time PCR targeting the katG and gyrA genes

Journal of Microbiological Methods
Laura RindiCarlo Garzelli

Abstract

A duplex real-time PCR assay was developed for the assignment of Mycobacterium tuberculosis isolates to the three genotypic groups based on the katG463/gyrA95 polymorphism. The assay was as sensitive and specific as nucleotide sequencing and proved also able to detect unambiguously the isolate genotype in clinical specimens.

References

Jun 7, 2003·Journal of Clinical Microbiology·James T DouglasKristin Kremer
Dec 12, 2003·The New England Journal of Medicine·Lisa S RosenblumJack T Crawford

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Citations

Mar 14, 2008·Journal of Clinical Microbiology·Teruyuki TakahashiToshiaki Takasu
Mar 7, 2006·Journal of Clinical Microbiology·Teruyuki Takahashi, Tomohiro Nakayama
Aug 8, 2009·The Journal of Molecular Diagnostics : JMD·Parameet KumarHanumanthappa K Prasad
Jul 25, 2007·Infection, Genetics and Evolution : Journal of Molecular Epidemiology and Evolutionary Genetics in Infectious Diseases·Csaba KödmönAkos Somoskövi
Mar 14, 2007·Journal of the Neurological Sciences·Teruyuki TakahashiHiroki Nagase
Jun 26, 2012·Infection, Genetics and Evolution : Journal of Molecular Epidemiology and Evolutionary Genetics in Infectious Diseases·Laura RindiCarlo Garzelli
Apr 6, 2006·Journal of Medical Microbiology·Nicoletta LariCarlo Garzelli

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