PMID: 6539272Apr 1, 1984Paper

Detection of N-nitrosamines in the saliva of habitual chewers of tobacco

Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association
A T SipahimalaniJ Nair

Abstract

The saliva of habitual chewers of tobacco and of non- chewers was examined using high-performance liquid chromatography and gas-liquid chromatography-thermal energy analysis. N-Nitrosodimethylamine, N-nitrosodiethylamine, N-nitrosopyrrolidine, N-nitrosonornicotine and N- nitrosohydroxyproline were detected in the saliva from the tobacco chewers . These N-nitroso compounds are probably leached from the tobacco itself and/or are formed in situ by the nitrosation of tobacco alkaloids as well as that of secondary amines. No N-nitroso compounds were detected in the saliva of non- chewers .

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Citations

Jul 1, 1992·Mutation Research·B C Dash, R K Das
Apr 1, 1986·Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association·S V BhideR Preussmann
Oct 1, 1988·Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association·A R TrickerR Preussmann
Sep 1, 1990·Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association·B G Osterdahl
Aug 1, 1989·Cancer Letters·A R Tricker, R Preussmann
Oct 1, 1989·Journal of Ethnopharmacology·S SenA Sharma
Oct 1, 1988·Food Additives and Contaminants·B G Osterdahl, S Slorach
Feb 28, 2014·Journal of Oral and Maxillofacial Pathology : JOMFP·Vaishali ShendeN Akarte
Oct 1, 1984·Food Additives and Contaminants·B G Osterdahl, S Slorach
Feb 1, 1989·Journal of Oral Pathology & Medicine : Official Publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology·S Y Chen

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