Detection of non-palpable breast cancer in asymptomatic women by using unenhanced diffusion-weighted and T2-weighted MR imaging: comparison with mammography and dynamic contrast-enhanced MR imaging.

European Radiology
Hidetake YabuuchiHiroshi Honda

Abstract

To compare the detectability of non-palpable breast cancer in asymptomatic women by using mammography (MMG), dynamic contrast-enhanced MR imaging (DCE-MRI) and unenhanced MR imaging with combined diffusion-weighted and T2-weighted images (DWI+T2WI). Forty-two lesions in 42 patients with non-palpable breast cancer in asymptomatic women were enrolled. For the reading test, we prepared a control including 13 normal and 8 benign cases. Each imaging set included biplane MMG, DCE-MRI and DWI+T2WI. Five readers were asked to rate the images on a scale of 0 to 100 for the likelihood of the presence of cancer and the BI-RADS category. Confidence level results were used to construct receiver operating characteristic analysis. Sensitivity and specificity were calculated for each technique. DWI+T2WI showed higher observer performances (area under the curve, AUC, 0.73) and sensitivity (50%) for the detection of non-palpable breast cancer than MMG alone (AUC 0.64; sensitivity 40%) but lower than those of DCE-MRI (AUC 0.93; sensitivity 86%). A combination of MMG and DWI+T2WI exhibited higher sensitivity (69%) compared with that of MMG alone (40%). DWI+T2WI could be useful in screening breast cancer for patients who cannot receive contrast med...Continue Reading

References

Jul 12, 2002·Journal of Magnetic Resonance Imaging : JMRI·Shantanu SinhaLawrence W Bassett
Aug 31, 2002·Journal of Magnetic Resonance Imaging : JMRI·Yong GuoJia-Hong Gao
Aug 23, 2003·AJR. American Journal of Roentgenology·Elizabeth A MorrisD David Dershaw
Jul 30, 2004·The New England Journal of Medicine·Mieke KriegeUNKNOWN Magnetic Resonance Imaging Screening Study Group
Sep 16, 2004·JAMA : the Journal of the American Medical Association·Ellen WarnerSteven A Narod
Nov 19, 2005·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Christiane K KuhlHans H Schild
Mar 30, 2007·The New England Journal of Medicine·Constance D LehmanUNKNOWN ACRIN Trial 6667 Investigators Group
May 19, 2007·Magnetic Resonance in Medical Sciences : MRMS : an Official Journal of Japan Society of Magnetic Resonance in Medicine·Seiko Kuroki-SuzukiMasatoshi Okazaki
Aug 8, 2007·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·S J LordN Houssami
Oct 10, 2007·Korean Journal of Radiology : Official Journal of the Korean Radiological Society·Mi Jung ParkJun Hyun Baik

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Citations

Feb 20, 2016·Journal of Magnetic Resonance Imaging : JMRI·Bachir TaouliDow-Mu Koh
Aug 10, 2013·Magnetic Resonance Imaging Clinics of North America·Savannah C Partridge, Elizabeth S McDonald
May 7, 2013·Magnetic Resonance Imaging Clinics of North America·Alice C BrandãoSavannah C Partridge
Nov 29, 2015·Magnetic Resonance Imaging Clinics of North America·Habib Rahbar, Savannah C Partridge
Feb 24, 2012·Journal of Magnetic Resonance Imaging : JMRI·Toshiki KazamaHideyuki Takano
Jul 17, 2013·Magnetic Resonance in Medical Sciences : MRMS : an Official Journal of Japan Society of Magnetic Resonance in Medicine·Reiko WoodhamsMasanori Ozaki
Oct 1, 2016·Journal of Magnetic Resonance Imaging : JMRI·Savannah C PartridgeEric E Sigmund
Mar 7, 2017·Journal of Magnetic Resonance Imaging : JMRI·Milica MedvedGregory S Karczmar
May 5, 2017·Journal of Magnetic Resonance Imaging : JMRI·Anika L McGrathHabib Rahbar
Oct 27, 2017·Breast Cancer Research : BCR·Jinchao FengKeith D Paulsen
Dec 15, 2017·Journal of Cancer Research and Therapeutics·Yueqiao Zhang, Hong Ren
May 16, 2014·World Journal of Clinical Oncology·Gisela Lg MenezesMaurice Aaj van den Bosch
Sep 9, 2018·Journal of Magnetic Resonance Imaging : JMRI·Doris LeithnerKatja Pinker
Oct 18, 2018·Journal of Magnetic Resonance Imaging : JMRI·Katerina Deike-HofmannSebastian Bickelhaupt
Mar 19, 2019·Magnetic Resonance in Medical Sciences : MRMS : an Official Journal of Japan Society of Magnetic Resonance in Medicine·Shinichiro SekiYoshiharu Ohno
Oct 9, 2019·Radiology·Nita AmornsiripanitchSavannah C Partridge
Sep 15, 2019·Journal of Magnetic Resonance Imaging : JMRI·Mami IimaKaori Togashi
Jun 20, 2013·Oncology Reports·Hiroshi KobayashiMiyuki Matsuura
Jan 16, 2020·Breast Cancer Research and Treatment·Anna RotiliFrancesco Sardanelli
Aug 5, 2019·Cancer Causes & Control : CCC·John T BrintonDeborah H Glueck
May 8, 2018·Journal of Magnetic Resonance Imaging : JMRI·Sibel KulOguzhan Ozdemir

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